Literature DB >> 26778694

Exploring the use of nanocarrier systems to deliver the magical molecule; Curcumin and its derivatives.

Mina Mehanny1, Rania M Hathout2, Ahmed S Geneidi1, Samar Mansour3.   

Abstract

Curcumin and its derivatives; curcuminoids have been proven as potential remedies in different diseases. However, their delivery carries several challenges owing to their poor aqueous solubility, photodegradation, chemical instability, poor bioavailability and rapid metabolism. This review explores and criticizes the numerous attempts that were adopted through the years to entrap/encapsulate this valuable drug in nanocarriers aiming to reach its most appropriate and successful delivery system.
Copyright © 2016 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Curcumin; Curcuminoids; Drug delivery; Nanocarriers

Mesh：

Substances：

Year:  2016        PMID： 26778694     DOI： 10.1016/j.jconrel.2016.01.018

Source DB:  PubMed          Journal:  J Control Release        ISSN： 0168-3659            Impact factor:   9.776


  24 in total

Review 1.  Regulation of Gene Expression through Food-Curcumin as a Sirtuin Activity Modulator.

Authors:  Anca Ungurianu; Anca Zanfirescu; Denisa Margină
Journal:  Plants (Basel)       Date:  2022-06-30

Review 2.  Curcumin, a Compound from Natural Sources, a True Scientific Challenge - A Review.

Authors:  Zorka Stanić
Journal:  Plant Foods Hum Nutr       Date:  2017-03       Impact factor: 4.124

3.  Discovery of a new function of curcumin which enhances its anticancer therapeutic potency.

Authors:  Koji Nagahama; Tomoya Utsumi; Takayuki Kumano; Saeko Maekawa; Naho Oyama; Junji Kawakami
Journal:  Sci Rep       Date:  2016-08-01       Impact factor: 4.379

4.  Tocotrienol Nanoemulsion Platform of Curcumin Elicit Elevated Apoptosis and Augmentation of Anticancer Efficacy against Breast and Ovarian Carcinomas.

Authors:  Nelson Steuber; Kathy Vo; Ritambhara Wadhwa; Jordan Birch; Paulina Iacoban; Pedro Chavez; Tamer A Elbayoumi
Journal:  Int J Mol Sci       Date:  2016-10-26       Impact factor: 5.923

5.  Micronization potentiates curcumin's anti-seizure effect and brings an important advance in epilepsy treatment.

Authors:  Kanandra Taisa Bertoncello; Gean Pablo S Aguiar; J Vladimir Oliveira; Anna Maria Siebel
Journal:  Sci Rep       Date:  2018-02-08       Impact factor: 4.379

6.  Antimalarial Activity of Orally Administered Curcumin Incorporated in Eudragit®-Containing Liposomes.

Authors:  Elisabet Martí Coma-Cros; Arnau Biosca; Elena Lantero; Maria Letizia Manca; Carla Caddeo; Lucía Gutiérrez; Miriam Ramírez; Livia Neves Borgheti-Cardoso; Maria Manconi; Xavier Fernàndez-Busquets
Journal:  Int J Mol Sci       Date:  2018-05-04       Impact factor: 5.923

7.  Encapsulation of Gold Nanostructures and Oil-in-Water Nanocarriers in Microgels with Biomedical Potential.

Authors:  Mariela Inostroza-Riquelme; Andrea Vivanco; Pablo Lara; Simón Guerrero; Edison Salas-Huenuleo; Alejandro Chamorro; Lisette Leyton; Karen Bolaños; Eyleen Araya; Andrew F G Quest; Marcelo J Kogan; Felipe Oyarzun-Ampuero
Journal:  Molecules       Date:  2018-05-18       Impact factor: 4.411

8.  Beneficial effects of curcumin nano-emulsion on spermatogenesis and reproductive performance in male rats under protein deficient diet model: enhancement of sperm motility, conservancy of testicular tissue integrity, cell energy and seminal plasma amino acids content.

Authors:  Omar A H Ahmed-Farid; Maha Nasr; Rania F Ahmed; Rofanda M Bakeer
Journal:  J Biomed Sci       Date:  2017-09-02       Impact factor: 8.410

9.  Delivery of curcumin by directed self-assembled micelles enhances therapeutic treatment of non-small-cell lung cancer.

Authors:  Wen-Ting Zhu; Sheng-Yao Liu; Lei Wu; Hua-Li Xu; Jun Wang; Guo-Xin Ni; Qing-Bing Zeng
Journal:  Int J Nanomedicine       Date:  2017-04-03

Review 10.  Molecular Mechanisms Underlying Curcumin-Mediated Therapeutic Effects in Type 2 Diabetes and Cancer.

Authors:  Marzena Wojcik; Michal Krawczyk; Pawel Wojcik; Katarzyna Cypryk; Lucyna Alicja Wozniak
Journal:  Oxid Med Cell Longev       Date:  2018-03-20       Impact factor: 6.543
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