Literature DB >> 2675521

Effect of age on the binding of lectin 125I-PHA-B to pancreatic islets of rat in vitro and stimulation of some cellular events.

P Khalid1, F Ahmad, M M Khan, A K Rastogi, J R Kidwai.   

Abstract

Agaricus bisporus lectin (PHA-B) stimulates insulin release in vitro. The stimulation is associated with increased conversion of proinsulin to insulin in the isolated islets of Langerhans of rats. Both these functions are directly proportional to the binding of I125 PHA-B, which is more marked in the islets from younger rats. The lectin binding to islets is not affected by glucose concentration in the medium.

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Year:  1989        PMID: 2675521     DOI: 10.1007/bf02581369

Source DB:  PubMed          Journal:  Acta Diabetol Lat        ISSN: 0001-5563


  12 in total

1.  Amino acid metabolism in mammalian cell cultures.

Authors:  H EAGLE
Journal:  Science       Date:  1959-08-21       Impact factor: 47.728

2.  Phytohemagglutinin: an initiator of mitosis in cultures of normal human leukocytes.

Authors:  P C NOWELL
Journal:  Cancer Res       Date:  1960-05       Impact factor: 12.701

3.  The binding of phytohemagglutinins to human platelet plasma membranes.

Authors:  P W Majerus; G N Brodie
Journal:  J Biol Chem       Date:  1972-07-10       Impact factor: 5.157

4.  Stimulation of glucose metabolism by lectins in isolated white fat cells.

Authors:  M P Czech; W S Lynn
Journal:  Biochim Biophys Acta       Date:  1973-02-28

5.  Method for the isolation of intact islets of Langerhans from the rat pancreas.

Authors:  P E Lacy; M Kostianovsky
Journal:  Diabetes       Date:  1967-01       Impact factor: 9.461

6.  Effect of lectins on hormone release from isolated rat islets of langerhans.

Authors:  R B Ewart; S Kornfeld; D M Kipnis
Journal:  Diabetes       Date:  1975-08       Impact factor: 9.461

7.  Purification of hemagglutinins from Agaricus bisporus by affinity chromatography.

Authors:  N Ahmad; R Bansal; A Ahmad; A K Rastogi; J R Kidwai
Journal:  Indian J Biochem Biophys       Date:  1984-08       Impact factor: 1.918

8.  Effect of age on proinsulin and insulin secretory patterns in isolated rat islets.

Authors:  G Gold; G M Reaven; E P Reaven
Journal:  Diabetes       Date:  1981-01       Impact factor: 9.461

9.  Effect of age on glucose-stimulated insulin release by the beta-cell of the rat.

Authors:  E P Reaven; G Gold; G M Reaven
Journal:  J Clin Invest       Date:  1979-08       Impact factor: 14.808

10.  Effect of age on Agaricus bisporus PHA-B stimulated insulin release and 45Ca2+ uptake in vitro by islets of Langerhans.

Authors:  N Ahmad; M M Khan; A K Rastogi; J R Kidwai
Journal:  Acta Diabetol Lat       Date:  1984 Oct-Dec
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