Literature DB >> 2675424

Bacteriophage introns: parasites within parasites?

M Belfort.   

Abstract

Several bacteriophage introns carry the information necessary to perform a complex series of RNA as well as DNA rearrangements. The RNA splicing reactions allow expression of the intron-containing genes, whereas recombination at the DNA level results in the mobility and invasive potential of the introns. The RNA and DNA transactions are temporally regulated to permit timely splicing early in infection, and expression of intron-encoded DNA endonucleases involved in mobility at late times. This is achieved through efficient use of the viral regulatory machinery, ensuring the perpetuation of the 'parasitic' introns.

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Year:  1989        PMID: 2675424     DOI: 10.1016/0168-9525(89)90083-8

Source DB:  PubMed          Journal:  Trends Genet        ISSN: 0168-9525            Impact factor:   11.639


  16 in total

Review 1.  Barriers to intron promiscuity in bacteria.

Authors:  D R Edgell; M Belfort; D A Shub
Journal:  J Bacteriol       Date:  2000-10       Impact factor: 3.490

2.  A new specific DNA endonuclease activity in yeast mitochondria.

Authors:  B Sargueil; A Delahodde; D Hatat; G L Tian; J Lazowska; C Jacq
Journal:  Mol Gen Genet       Date:  1991-02

3.  Base pairing between the 3' exon and an internal guide sequence increases 3' splice site specificity in the Tetrahymena self-splicing rRNA intron.

Authors:  E R Suh; R B Waring
Journal:  Mol Cell Biol       Date:  1990-06       Impact factor: 4.272

4.  Scientific serendipity initiates an intron odyssey.

Authors:  Marlene Belfort
Journal:  J Biol Chem       Date:  2009-08-26       Impact factor: 5.157

5.  Intron mobility in phage T4 is dependent upon a distinctive class of endonucleases and independent of DNA sequences encoding the intron core: mechanistic and evolutionary implications.

Authors:  D Bell-Pedersen; S Quirk; J Clyman; M Belfort
Journal:  Nucleic Acids Res       Date:  1990-07-11       Impact factor: 16.971

6.  Genetic definition of a protein-splicing domain: functional mini-inteins support structure predictions and a model for intein evolution.

Authors:  V Derbyshire; D W Wood; W Wu; J T Dansereau; J Z Dalgaard; M Belfort
Journal:  Proc Natl Acad Sci U S A       Date:  1997-10-14       Impact factor: 11.205

Review 7.  Enigmatic distribution, evolution, and function of inteins.

Authors:  Olga Novikova; Natalya Topilina; Marlene Belfort
Journal:  J Biol Chem       Date:  2014-04-02       Impact factor: 5.157

8.  Unexpected abundance of self-splicing introns in the genome of bacteriophage Twort: introns in multiple genes, a single gene with three introns, and exon skipping by group I ribozymes.

Authors:  M Landthaler; D A Shub
Journal:  Proc Natl Acad Sci U S A       Date:  1999-06-08       Impact factor: 11.205

Review 9.  Prokaryotic introns and inteins: a panoply of form and function.

Authors:  M Belfort; M E Reaban; T Coetzee; J Z Dalgaard
Journal:  J Bacteriol       Date:  1995-07       Impact factor: 3.490

10.  Requirements for self-splicing of a group I intron from Physarum polycephalum.

Authors:  G A Rocheleau; S A Woodson
Journal:  Nucleic Acids Res       Date:  1994-10-11       Impact factor: 16.971

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