Rayzel Shulman1,2,3, Therese A Stukel2,3, Fiona A Miller2,4, Alice Newman3, Denis Daneman1, Astrid Guttmann1,2,3. 1. Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, Canada. 2. Institute of Health Policy, Management and Evaluation, University of Toronto, Health Sciences Building, Toronto, Canada. 3. Institute for Clinical Evaluative Sciences, Toronto, Canada. 4. Toronto Health Economics and Technology Assessment (THETA) Collaborative, Toronto, Canada.
Abstract
OBJECTIVE: To describe insulin pump use by youth since introduction of universal funding in Ontario, Canada and to explore the relationship between pump use and pediatric diabetes center characteristics and the relationship between discontinuation and center and patient characteristics. RESEARCH DESIGN AND METHODS: Observational, population-based cohort study of youth with type 1 diabetes (<19 yr) who received pump funding from 2006 to 2013 (n = 3700). We linked 2012 survey data from 33 pediatric diabetes centers to health administrative databases. We tested the relationship between center-level pump uptake and center characteristics (center type, physician model, and availability of 24-h support) using an adjusted negative binomial model; we studied center- and patient-level factors (socioeconomic status and baseline glycemic control) associated with discontinuation using a Cox proportional hazards model with generalized estimating equations. RESULTS: Pump users were more likely to be in the highest income quintile than non-pump users (29.6 vs. 19.1%, p < 0.0001). In 2012, mean percent pump use was 38.0% with variability across centers. There was no association between uptake and center characteristics. Discontinuation was low (0.42/100 person-yr) and was associated with being followed at a small community center [hazard ratio (HR): 2.24 (1.05-4.76)] and being more deprived [HR: 2.36 (1.14-1.48)]. Older age was associated with a lower rate of discontinuation [HR: 0.31 (0.14-0.66)]. CONCLUSIONS: Rates of pump use have increased since 2006 and discontinuation is rare. Large variation in uptake across centers was not explained by the factors we examined but may reflect variation in patient populations or practice patterns, and should be further explored.
OBJECTIVE: To describe insulin pump use by youth since introduction of universal funding in Ontario, Canada and to explore the relationship between pump use and pediatric diabetes center characteristics and the relationship between discontinuation and center and patient characteristics. RESEARCH DESIGN AND METHODS: Observational, population-based cohort study of youth with type 1 diabetes (<19 yr) who received pump funding from 2006 to 2013 (n = 3700). We linked 2012 survey data from 33 pediatric diabetes centers to health administrative databases. We tested the relationship between center-level pump uptake and center characteristics (center type, physician model, and availability of 24-h support) using an adjusted negative binomial model; we studied center- and patient-level factors (socioeconomic status and baseline glycemic control) associated with discontinuation using a Cox proportional hazards model with generalized estimating equations. RESULTS: Pump users were more likely to be in the highest income quintile than non-pump users (29.6 vs. 19.1%, p < 0.0001). In 2012, mean percent pump use was 38.0% with variability across centers. There was no association between uptake and center characteristics. Discontinuation was low (0.42/100 person-yr) and was associated with being followed at a small community center [hazard ratio (HR): 2.24 (1.05-4.76)] and being more deprived [HR: 2.36 (1.14-1.48)]. Older age was associated with a lower rate of discontinuation [HR: 0.31 (0.14-0.66)]. CONCLUSIONS: Rates of pump use have increased since 2006 and discontinuation is rare. Large variation in uptake across centers was not explained by the factors we examined but may reflect variation in patient populations or practice patterns, and should be further explored.
Authors: Jenise C Wong; Claire Boyle; Linda A DiMeglio; Lucy D Mastrandrea; Kimber-Lee Abel; Eda Cengiz; Pinar A Cemeroglu; Grazia Aleppo; Joseph F Largay; Nicole C Foster; Roy W Beck; Saleh Adi Journal: J Diabetes Sci Technol Date: 2016-09-25
Authors: Yun Jeong Lee; Young Ah Lee; Jae Hyun Kim; Hye Rim Chung; Min Jeong Gu; Ji Young Kim; Choong Ho Shin Journal: Ann Pediatr Endocrinol Metab Date: 2020-12-31
Authors: Rayzel Shulman; Therese A Stukel; Fiona A Miller; Alice Newman; Denis Daneman; Jonathan D Wasserman; Astrid Guttmann Journal: BMJ Open Diabetes Res Care Date: 2016-06-22