| Literature DB >> 26748753 |
Jeroen Leijten1, Ali Khademhosseini2.
Abstract
Stem cells respond to nanoscale, microscale, and macroscale cues, such as matrix, growth factors, and niche organization, which are difficult to physiologically recapitulate in culture. We discuss how utilizing bioengineering approaches to manipulate and integrate spatiotemporal cues across these discrete length scales can improve traditional methods for controlling cell fate.Mesh：
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Year: 2016 PMID： 26748753 DOI： 10.1016/j.stem.2015.12.013
Source DB: PubMed Journal: Cell Stem Cell ISSN： 1875-9777 Impact factor: 24.633