Seockhoon Chung1, Elise K Hodges2, Deborah L Ruzicka3, Timothy F Hoban4, Susan L Garetz5, Kenneth E Guire6, Barbara T Felt7, James E Dillon8, Ronald D Chervin3, Bruno Giordani9. 1. Sleep Disorders Center, Ann Arbor, MI, USA; Department of Neurology, Ann Arbor, MI, USA; Department of Psychiatry, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea. Electronic address: schung@amc.seoul.kr. 2. Neuropsychology Section, Department of Psychiatry, Ann Arbor, MI, USA. 3. Sleep Disorders Center, Ann Arbor, MI, USA; Department of Neurology, Ann Arbor, MI, USA. 4. Sleep Disorders Center, Ann Arbor, MI, USA; Department of Pediatrics and Communicable Diseases, Ann Arbor, MI, USA. 5. Sleep Disorders Center, Ann Arbor, MI, USA; Department of Otolaryngology/Head and Neck Surgery, Ann Arbor, MI, USA. 6. Department of Biostatistics, Ann Arbor, MI, USA. 7. Sleep Disorders Center, Ann Arbor, MI, USA; Division of Child Behavioral Health, Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI, USA. 8. Department of Psychiatry, Central Michigan University College of Medicine, Saginaw, MI, USA. 9. Department of Neurology, Ann Arbor, MI, USA; Neuropsychology Section, Department of Psychiatry, Ann Arbor, MI, USA.
Abstract
OBJECTIVES: To examine whether high intellectual ability, in comparison to average or lower performance, reflects the consequences of sleep-disordered breathing and limits behavioral benefit observed 6 months after adenotonsillectomy. METHODS: Children aged 3-12 years (n=147) recruited from otolaryngology practices at two hospitals and assessed with Conners' Parent Rating Scales and an age range-appropriate intellectual measure, the Stanford-Binet Intelligence Scale at baseline and 6 months after clinically-indicated adenotonsillectomy. Subjects were classified as having high (IQ≥110), average (90≤IQ<110), or low (IQ<90) cognitive ability. RESULTS: After adenotonsillectomy, improvements in Conners' internalizing, externalizing, hyperactivity, and cognitive domains were observed across IQ groups (main effects for time, all p<0.01 or better), with no evidence for differential improvements among the groups (no significant time by IQ group interactions). The magnitude of behavioral improvement among children with high IQ resembled that observed among the other two groups. Changes in the Conners' domains were not significantly correlated with baseline IQ, age, socioeconomic status, body mass index z-score, or respiratory disturbance index. CONCLUSION: Behavioral function can improve after adenotonsillectomy even among children with relatively high intellectual ability at baseline. Diagnosis and treatment with expectation of neurobehavioral benefit should be considered among high-performing children as readily as it is more traditionally among their lower-performing peers.
OBJECTIVES: To examine whether high intellectual ability, in comparison to average or lower performance, reflects the consequences of sleep-disordered breathing and limits behavioral benefit observed 6 months after adenotonsillectomy. METHODS:Children aged 3-12 years (n=147) recruited from otolaryngology practices at two hospitals and assessed with Conners' Parent Rating Scales and an age range-appropriate intellectual measure, the Stanford-Binet Intelligence Scale at baseline and 6 months after clinically-indicated adenotonsillectomy. Subjects were classified as having high (IQ≥110), average (90≤IQ<110), or low (IQ<90) cognitive ability. RESULTS: After adenotonsillectomy, improvements in Conners' internalizing, externalizing, hyperactivity, and cognitive domains were observed across IQ groups (main effects for time, all p<0.01 or better), with no evidence for differential improvements among the groups (no significant time by IQ group interactions). The magnitude of behavioral improvement among children with high IQ resembled that observed among the other two groups. Changes in the Conners' domains were not significantly correlated with baseline IQ, age, socioeconomic status, body mass index z-score, or respiratory disturbance index. CONCLUSION: Behavioral function can improve after adenotonsillectomy even among children with relatively high intellectual ability at baseline. Diagnosis and treatment with expectation of neurobehavioral benefit should be considered among high-performing children as readily as it is more traditionally among their lower-performing peers.
Authors: Michael S Urschitz; Anke Guenther; Esther Eggebrecht; Judith Wolff; Pilar M Urschitz-Duprat; Martin Schlaud; Christian F Poets Journal: Am J Respir Crit Care Med Date: 2003-05-28 Impact factor: 21.405
Authors: Daniel J Gottlieb; Cynthia Chase; Richard M Vezina; Timothy C Heeren; Michael J Corwin; Sanford H Auerbach; Debra E Weese-Mayer; Samuel M Lesko Journal: J Pediatr Date: 2004-10 Impact factor: 4.406
Authors: Ronald D Chervin; Dave F Clarke; Jennifer L Huffman; Erica Szymanski; Deborah L Ruzicka; Vnona Miller; Arie L Nettles; MaryFran R Sowers; Bruno J Giordani Journal: Sleep Med Date: 2003-01 Impact factor: 3.492
Authors: Carole L Marcus; Reneé H Moore; Carol L Rosen; Bruno Giordani; Susan L Garetz; H Gerry Taylor; Ron B Mitchell; Raouf Amin; Eliot S Katz; Raanan Arens; Shalini Paruthi; Hiren Muzumdar; David Gozal; Nina Hattiangadi Thomas; Janice Ware; Dean Beebe; Karen Snyder; Lisa Elden; Robert C Sprecher; Paul Willging; Dwight Jones; John P Bent; Timothy Hoban; Ronald D Chervin; Susan S Ellenberg; Susan Redline Journal: N Engl J Med Date: 2013-05-21 Impact factor: 91.245
Authors: David Gozal; Barry W Row; Evelyne Gozal; Leila Kheirandish; Jennifer J Neville; Kenneth R Brittian; Leroy R Sachleben; Shang Z Guo Journal: Eur J Neurosci Date: 2003-10 Impact factor: 3.386
Authors: Alexa J Watach; Chanelle T Bishop-Gilyard; Helen Ku; Olufunke Afolabi-Brown; Elizabeth Prout Parks; Melissa S Xanthopoulos Journal: Health Educ J Date: 2022-05-04