Literature DB >> 26744717

Common Statistical Mistakes in Descriptive Statistics Reports of Normal and Non-Normal Variables in Biomedical Sciences Research.

Farzan Madadizadeh1, Mohamad Ezati Asar2, Mostafa Hosseini3.   

Abstract

Entities:  

Year:  2015        PMID: 26744717      PMCID: PMC4703239     

Source DB:  PubMed          Journal:  Iran J Public Health        ISSN: 2251-6085            Impact factor:   1.429


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Dear Editor in Chief Statistics are the aids of researchers, and the proper use of them requires sufficient knowledge of theoretical and applied concepts of statistics (1). Today, with the advances in science and the help of computer, statistical analysis tools of data research are easily accessible to any researcher and researchers obtain output and report it in their research without having enough information by selecting a number of options from these black boxes (statistical software). The lack of correct writing of some statistical indicators has been one of the known problems in medical sciences literature in recent years, E.G., standard deviation and the wrong replacement of that with standard error in articles (2). This is so important that for some valid journals the measure of article acceptance is to pinpoint these indicators. Standard deviation is an indicator of descriptive statistics that describes the distribution of sample data around their mean (3). x : Data of i-th observation x¯ : mean of observations, n = sample size The standard error is an indicator of inferential statistics to extend the sample results to the population from which the sample was extracted. In other words, this indicator reflects the credibility and reliability of the research and answers the question what the dispersion of results will be if a sample with the same size and by substitution is selected in other times from the same initial population, for example, if the goal is to generalize the results of the sample mean to the population mean, to evaluate the validity of the study after re-sampling for n times and to calculate the means of the sample, their dispersion around the total mean is the standard error (4). But in practice, apart from wasting time, re-sampling technique would be a waste of cost, thus the following simple equation is used to calculate the standard error (5). The standard error is always less than the standard deviation and medical researchers sometimes report it mistakenly instead of the standard deviation in descriptive statistics of the study variables, this will distract readers from seeing the dispersion and the research data seems better (3, 5). The standard deviation alone is meaningful and it is essential to present it in descriptive statistics of normal quantitative variables but the standard error alone is meaningless and it is used only to build confidence interval (6). Another problem is that some researchers without evaluating the normality of quantitative variable begin to report the descriptive indicators of the variable. It should be noted that standard deviation is only valuable to describe the dispersion in normal quantitative variables and in a case that the variable is not normally distributed another dispersion indicator called interquartile range (IQR= Q3-Q1) is used. Based on dividing a data set into quartiles, the first quartile, denoted Q1, is the value in the data set that holds 25% of the values below it. The third quartile, denoted Q3, is the value in the data set that holds 75% of the values below it (1, 7). Another problem is the final reporting in the form of x¯ ± SD that creates confusion with the confidence interval for the mean , it is recommended to avoid confusion that the results of descriptive statistics are presented for the normal variables as mean(SD) and for non-normal variables as median(IQR) (8). In short, respecting the above tips in addition to raising the quality of papers and journals, can significantly contribute to the improvement of health systems research, reduce the production of low-quality articles and thus reduce waste of health care system costs in the field of research. accordingly, given that a major concern of the Ministry of Health and its policy makers is to reduce costs and increase productivity and improve the quality of health systems research, it is recommended that researchers and practitioners of health care system publications pay more attention to these points, through which the high costs of health care system can be controlled and reduced.
  8 in total

1.  Misuse of standard error of the mean (SEM) when reporting variability of a sample. A critical evaluation of four anaesthesia journals.

Authors:  P Nagele
Journal:  Br J Anaesth       Date:  2003-04       Impact factor: 9.166

Review 2.  The use and misuse of statistical methodologies in pharmacology research.

Authors:  Michael J Marino
Journal:  Biochem Pharmacol       Date:  2013-06-04       Impact factor: 5.858

3.  In brief: Standard deviation and standard error.

Authors:  David J Biau
Journal:  Clin Orthop Relat Res       Date:  2011-05-10       Impact factor: 4.176

4.  Common misconceptions about data analysis and statistics.

Authors:  Harvey J Motulsky
Journal:  Br J Pharmacol       Date:  2014-09-26       Impact factor: 8.739

5.  Inappropriate use of standard error of the mean when reporting variability of study samples: a critical evaluation of four selected journals of obstetrics and gynecology.

Authors:  Wen-Ru Ko; Wei-Te Hung; Hui-Chin Chang; Long-Yau Lin
Journal:  Taiwan J Obstet Gynecol       Date:  2014-03       Impact factor: 1.705

6.  Misuse of the standard error of the mean.

Authors:  A Herxheimer
Journal:  Br J Clin Pharmacol       Date:  1988-08       Impact factor: 4.335

Review 7.  Standard deviation and standard error of the mean.

Authors:  Dong Kyu Lee; Junyong In; Sangseok Lee
Journal:  Korean J Anesthesiol       Date:  2015-05-28

8.  A standard error: distinguishing standard deviation from standard error.

Authors:  Rickey E Carter
Journal:  Diabetes       Date:  2013-08       Impact factor: 9.461

  8 in total
  5 in total

1.  Identification of discriminative gene-level and protein-level features associated with pathogenic gain-of-function and loss-of-function variants.

Authors:  Cigdem Sevim Bayrak; David Stein; Aayushee Jain; Kumardeep Chaudhary; Girish N Nadkarni; Tielman T Van Vleck; Anne Puel; Stephanie Boisson-Dupuis; Satoshi Okada; Peter D Stenson; David N Cooper; Avner Schlessinger; Yuval Itan
Journal:  Am J Hum Genet       Date:  2021-11-10       Impact factor: 11.043

2.  The Second Mediterranean Seminar on Science Writing, Editing and Publishing (SWEP - 2018), Sarajevo, December 8th, 2018.

Authors:  Izet Masic; Miro Jakovljevic; Osman Sinanovic; Srecko Gajovic; Mirko Spiroski; Rasim Jusufovic; Sekib Sokolovic; Besim Prnjavorac; Enver Zerem; Benjamin Djulbegovic; Selma Porovic; Slobodan Jankovic; Mirsad Hadzikadic; Lejla Zunic; Edin Begic; Edin Nislic; Nedim Begic; Emir Becirovic; Anis Cerovac; Venesa Skrijelj; Jasmina Nuhanovic
Journal:  Acta Inform Med       Date:  2018-12

3.  Recovery Room Cortisol Predicts Long-Term Glucocorticoid Need After Transsphenoidal Surgery for Pituitary Tumors.

Authors:  Amro Qaddoura; Tenzin N Shalung; Michael P Meier; Jeannette Goguen; Rowan Jing; Stanley Zhang; Kalman Kovacs; Michael D Cusimano
Journal:  Neurosurgery       Date:  2019-03-01       Impact factor: 4.654

Review 4.  How are growth hormone and insulin-like growth factor-1 reported as markers for drug effectiveness in clinical acromegaly research? A comprehensive methodologic review.

Authors:  Michiel J van Esdonk; Eline J M van Zutphen; Ferdinand Roelfsema; Alberto M Pereira; Piet H van der Graaf; Nienke R Biermasz; Jasper Stevens; Jacobus Burggraaf
Journal:  Pituitary       Date:  2018-06       Impact factor: 4.107

5.  Comment on pediatric living donor liver transplantation decade progress in Shanghai: Characteristics and risks factors of mortality.

Authors:  Sami Akbulut; Tevfik Tolga Sahin; Sezai Yilmaz
Journal:  World J Gastroenterol       Date:  2020-08-14       Impact factor: 5.742

  5 in total

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