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Literature DB >> 26744395

CELL BIOLOGY. Disrupted nuclear import-export in neurodegeneration.

Sandrine Da Cruz¹, Don W Cleveland².

Abstract

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2016 PMID： 26744395 PMCID： PMC4842317 DOI： 10.1126/science.aad9872

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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15 in total

1. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.

Authors: Montserrat Arrasate; Siddhartha Mitra; Erik S Schweitzer; Mark R Segal; Steven Finkbeiner
Journal: Nature Date: 2004-10-14 Impact factor: 49.962

2. Opposing activities protect against age-onset proteotoxicity.

Authors: Ehud Cohen; Jan Bieschke; Rhonda M Perciavalle; Jeffery W Kelly; Andrew Dillin
Journal: Science Date: 2006-08-10 Impact factor: 47.728

3. Compartment-specific aggregases direct distinct nuclear and cytoplasmic aggregate deposition.

Authors: Stephanie B M Miller; Chi-Ting Ho; Juliane Winkler; Maria Khokhrina; Annett Neuner; Mohamed Y H Mohamed; D Lys Guilbride; Karsten Richter; Michael Lisby; Elmar Schiebel; Axel Mogk; Bernd Bukau
Journal: EMBO J Date: 2015-02-11 Impact factor: 11.598

4. RAN Translation in Huntington Disease.

Authors: Monica Bañez-Coronel; Fatma Ayhan; Alex D Tarabochia; Tao Zu; Barbara A Perez; Solaleh Khoramian Tusi; Olga Pletnikova; David R Borchelt; Christopher A Ross; Russell L Margolis; Anthony T Yachnis; Juan C Troncoso; Laura P W Ranum
Journal: Neuron Date: 2015-11-18 Impact factor: 17.173

5. The C9orf72 repeat expansion disrupts nucleocytoplasmic transport.

Authors: Ke Zhang; Christopher J Donnelly; Thomas E Lloyd; Jeffrey D Rothstein; Aaron R Haeusler; Jonathan C Grima; James B Machamer; Peter Steinwald; Elizabeth L Daley; Sean J Miller; Kathleen M Cunningham; Svetlana Vidensky; Saksham Gupta; Michael A Thomas; Ingie Hong; Shu-Ling Chiu; Richard L Huganir; Lyle W Ostrow; Michael J Matunis; Jiou Wang; Rita Sattler
Journal: Nature Date: 2015-08-26 Impact factor: 49.962

6. GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport.

Authors: Brian D Freibaum; Yubing Lu; Rodrigo Lopez-Gonzalez; Nam Chul Kim; Sandra Almeida; Kyung-Ha Lee; Nisha Badders; Marc Valentine; Bruce L Miller; Philip C Wong; Leonard Petrucelli; Hong Joo Kim; Fen-Biao Gao; J Paul Taylor
Journal: Nature Date: 2015-08-26 Impact factor: 49.962

7. Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA.

Authors: Andreas C Woerner; Frédéric Frottin; Daniel Hornburg; Li R Feng; Felix Meissner; Maria Patra; Jörg Tatzelt; Matthias Mann; Konstanze F Winklhofer; F Ulrich Hartl; Mark S Hipp
Journal: Science Date: 2015-12-03 Impact factor: 47.728

8. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

Authors: F Saudou; S Finkbeiner; D Devys; M E Greenberg
Journal: Cell Date: 1998-10-02 Impact factor: 41.582

9. Misfolded proteins partition between two distinct quality control compartments.

Authors: Daniel Kaganovich; Ron Kopito; Judith Frydman
Journal: Nature Date: 2008-08-28 Impact factor: 49.962

10. Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS.

Authors: Ana Jovičić; Jerome Mertens; Steven Boeynaems; Elke Bogaert; Noori Chai; Shizuka B Yamada; Joseph W Paul; Shuying Sun; Joseph R Herdy; Gregor Bieri; Nicholas J Kramer; Fred H Gage; Ludo Van Den Bosch; Wim Robberecht; Aaron D Gitler
Journal: Nat Neurosci Date: 2015-09 Impact factor: 24.884

8 in total

1. Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport.

Authors: Fatima Gasset-Rosa; Carlos Chillon-Marinas; Alexander Goginashvili; Ranjit Singh Atwal; Jonathan W Artates; Ricardos Tabet; Vanessa C Wheeler; Anne G Bang; Don W Cleveland; Clotilde Lagier-Tourenne
Journal: Neuron Date: 2017-04-05 Impact factor: 17.173

2. Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis.

Authors: Dara Ditsworth; Marcus Maldonado; Melissa McAlonis-Downes; Shuying Sun; Amanda Seelman; Kevin Drenner; Eveline Arnold; Shuo-Chien Ling; Donald Pizzo; John Ravits; Don W Cleveland; Sandrine Da Cruz
Journal: Acta Neuropathol Date: 2017-03-29 Impact factor: 17.088

CELL BIOLOGY. Disrupted nuclear import-export in neurodegeneration.

1. Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.

2. Opposing activities protect against age-onset proteotoxicity.

3. Compartment-specific aggregases direct distinct nuclear and cytoplasmic aggregate deposition.

4. RAN Translation in Huntington Disease.

5. The C9orf72 repeat expansion disrupts nucleocytoplasmic transport.

6. GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport.

7. Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA.

8. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

9. Misfolded proteins partition between two distinct quality control compartments.

10. Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS.

1. Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic Transport.

2. Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis.

3. Opportunities and challenges for the use of induced pluripotent stem cells in modelling neurodegenerative disease.

4. Differential Influence of Sample Sex and Neuronal Maturation on mRNA and Protein Transport in Induced Human Neurons.

Review 5. Proteostasis in the Male and Female Germline: A New Outlook on the Maintenance of Reproductive Health.

Review 6. Regulating Phase Transition in Neurodegenerative Diseases by Nuclear Import Receptors.

Review 7. The Rules and Functions of Nucleocytoplasmic Shuttling Proteins.

8. Nuclear envelope-vacuole contacts mitigate nuclear pore complex assembly stress.