Literature DB >> 26740575

Probability of atrial fibrillation after ablation: Using a parametric nonlinear temporal decomposition mixed effects model.

Jeevanantham Rajeswaran1, Eugene H Blackstone1, John Ehrlinger1, Liang Li2, Hemant Ishwaran3, Michael K Parides4.   

Abstract

Atrial fibrillation is an arrhythmic disorder where the electrical signals of the heart become irregular. The probability of atrial fibrillation (binary response) is often time varying in a structured fashion, as is the influence of associated risk factors. A generalized nonlinear mixed effects model is presented to estimate the time-related probability of atrial fibrillation using a temporal decomposition approach to reveal the pattern of the probability of atrial fibrillation and their determinants. This methodology generalizes to patient-specific analysis of longitudinal binary data with possibly time-varying effects of covariates and with different patient-specific random effects influencing different temporal phases. The motivation and application of this model is illustrated using longitudinally measured atrial fibrillation data obtained through weekly trans-telephonic monitoring from an NIH sponsored clinical trial being conducted by the Cardiothoracic Surgery Clinical Trials Network.

Entities:  

Keywords:  Binary longitudinal response; mixed effects model; multiphase model; nonlinear model; temporal decomposition; time varying coefficient

Mesh：

Year:  2016        PMID： 26740575      PMCID： PMC5633490          DOI： 10.1177/0962280215623583

Source DB:  PubMed          Journal:  Stat Methods Med Res        ISSN： 0962-2802            Impact factor:   3.021


  13 in total

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Authors:  A Marc Gillinov; Michael Argenziano; Eugene H Blackstone; Alexander Iribarne; Joseph J DeRose; Gorav Ailawadi; Mark J Russo; Deborah D Ascheim; Michael K Parides; Evelio Rodriguez; Denis Bouchard; Wendy C Taddei-Peters; Nancy L Geller; Michael A Acker; Annetine C Gelijns
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6.  Random-effects models for longitudinal data.

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  2 in total

1.  Biatrial maze procedure versus pulmonary vein isolation for atrial fibrillation during mitral valve surgery: New analytical approaches and end points.

Authors:  Eugene H Blackstone; Helena L Chang; Jeevanantham Rajeswaran; Michael K Parides; Hemant Ishwaran; Liang Li; John Ehrlinger; Annetine C Gelijns; Alan J Moskowitz; Michael Argenziano; Joseph J DeRose; Jean-Phillipe Couderc; Dan Balda; François Dagenais; Michael J Mack; Gorav Ailawadi; Peter K Smith; Michael A Acker; Patrick T O'Gara; A Marc Gillinov
Journal:  J Thorac Cardiovasc Surg       Date:  2018-07-27       Impact factor: 5.209

2.  Temporal trend and associated risk factors for new-onset atrial fibrillation following cardiac valve surgery.

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