| Literature DB >> 26740313 |
Min Shen1, Guangxin Luan1, Yanhong Wang1, Yaowen Chang2, Chi Zhang2, Jingni Yang1, Shanshan Deng3, Baodong Ling4, Xu Jia5.
Abstract
A total of 101 Acinetobacter baumannii isolates were collected to determine the mechanisms of quinolone resistance and investigate the occurrence of carbapenem and high-level aminoglycoside resistance genes among quinolone-resistant strains. Among 77 quinolone-resistant A. baumannii harbored mutations of gyrA and parC, 41 isolates, which belonged to European clone II, had resistance to aminoglycosides and carbapenems due to the expression of armA and acquisition of blaOXA-23. Most of sequence type belonged to clonal complex 92. These results suggested hospital dissemination of multidrug-resistant A. baumannii carrying blaOXA-23, armA, and mutations of quinolone resistance-determining regions in western China.Entities:
Keywords: Acinetobacter baumannii; Multi-drug resistant; Quinolone; armA; bla(OXA-23)
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Year: 2015 PMID： 26740313 DOI： 10.1016/j.diagmicrobio.2015.10.009
Source DB: PubMed Journal: Diagn Microbiol Infect Dis ISSN： 0732-8893 Impact factor: 2.803