Yen-Ting Lin1,2, Grégory Amouyal3, Jean-Michel Correas3,4, Héléna Pereira3, Olivier Pellerin3,5,6, Costantino Del Giudice3, Carole Déan3, Nicolas Thiounn7, Marc Sapoval3,5,6. 1. Assistance publique Hôpitaux de Paris. Hôpital Européen Georges-Pompidou, Vascular and Oncological Interventional Radiology, 20 rue Leblanc, 75015, Paris, France. ymerically@gmail.com. 2. Department of Radiology, Taichung Veterans General Hospital, No.1650, Taiwan Boulevard Sect. 4, Taichung City, Taiwan, Republic of China. ymerically@gmail.com. 3. Assistance publique Hôpitaux de Paris. Hôpital Européen Georges-Pompidou, Vascular and Oncological Interventional Radiology, 20 rue Leblanc, 75015, Paris, France. 4. Radiology Department, Hôpital Necker, 149 rue de Sèvres, 75015, Paris, France. 5. Inserm (Institut national de la santé et de la recherche médicale) U970, 56 rue Leblanc, 75015, Paris, France. 6. Université Paris Descartes, Sorbonne Paris-Cité, Paris, France. 7. Assistance publique Hopitaux de Paris, Hôpital Européen Georges-Pompidou, Urology, 20 rue Leblanc, 75015, Paris, France.
Abstract
OBJECTIVES: To assess the impact of prostatic arterial embolisation (PAE) on various prostate gland anatomical zones. METHODS: We retrospectively reviewed paired MRI scans obtained before and after PAE for 25 patients and evaluated changes in volumes of the median lobe (ML), central gland (CG), peripheral zone (PZ) and whole prostate gland (WPV) following PAE. We used manual segmentation to calculate volume on axial view T2-weighted images for ML, CG and WPV. We calculated PZ volume by subtracting CG volume from WPV. Enhanced phase on dynamic contrasted-enhanced MRI was used to evaluate the infarction areas after PAE. Clinical results of International Prostate Symptom Score and International Index of Erectile Function questionnaires and the urodynamic study were evaluated before and after PAE. RESULTS: Significant reductions in volume were observed after PAE for ML (26.2 % decrease), CG (18.8 %), PZ (16.4 %) and WPV (19.1 %; p < 0.001 for all these volumes). Patients with clinical failure had smaller volume reductions for WPV, ML and CG (all p < 0.05). Patients with significant CG infarction after PAE displayed larger WPV, ML and CG volume reductions (all p < 0.01). CONCLUSIONS: PAE can significantly decrease WPV, ML, CG and PZ volumes, and poor clinical outcomes are associated with smaller volume reductions. KEY POINTS: • The MRI segmentation method provides detailed comparisons of prostate volume change. • Prostatic arterial embolisation (PAE) decreased central gland and peripheral zone volumes. • Prostates with infarction after PAE showed larger decreases in volume. • A larger decrease in prostate volume is associated with clinical success.
OBJECTIVES: To assess the impact of prostatic arterial embolisation (PAE) on various prostate gland anatomical zones. METHODS: We retrospectively reviewed paired MRI scans obtained before and after PAE for 25 patients and evaluated changes in volumes of the median lobe (ML), central gland (CG), peripheral zone (PZ) and whole prostate gland (WPV) following PAE. We used manual segmentation to calculate volume on axial view T2-weighted images for ML, CG and WPV. We calculated PZ volume by subtracting CG volume from WPV. Enhanced phase on dynamic contrasted-enhanced MRI was used to evaluate the infarction areas after PAE. Clinical results of International Prostate Symptom Score and International Index of Erectile Function questionnaires and the urodynamic study were evaluated before and after PAE. RESULTS: Significant reductions in volume were observed after PAE for ML (26.2 % decrease), CG (18.8 %), PZ (16.4 %) and WPV (19.1 %; p < 0.001 for all these volumes). Patients with clinical failure had smaller volume reductions for WPV, ML and CG (all p < 0.05). Patients with significant CGinfarction after PAE displayed larger WPV, ML and CG volume reductions (all p < 0.01). CONCLUSIONS:PAE can significantly decrease WPV, ML, CG and PZ volumes, and poor clinical outcomes are associated with smaller volume reductions. KEY POINTS: • The MRI segmentation method provides detailed comparisons of prostate volume change. • Prostatic arterial embolisation (PAE) decreased central gland and peripheral zone volumes. • Prostates with infarction after PAE showed larger decreases in volume. • A larger decrease in prostate volume is associated with clinical success.
Authors: Julie C Bulman; Robert Toth; Amish D Patel; B Nicolas Bloch; Colm J McMahon; Long Ngo; Anant Madabhushi; Neil M Rofsky Journal: Radiology Date: 2012-01 Impact factor: 11.105
Authors: Baris Turkbey; Sergei V Fotin; Robert J Huang; Yin Yin; Dagane Daar; Omer Aras; Marcelino Bernardo; Brian E Garvey; Juanita Weaver; Hrishikesh Haldankar; Naira Muradyan; Maria J Merino; Peter A Pinto; Senthil Periaswamy; Peter L Choyke Journal: AJR Am J Roentgenol Date: 2013-11 Impact factor: 3.959
Authors: Sandeep Bagla; Cynthia P Martin; Arletta van Breda; Michael J Sheridan; Keith M Sterling; Dimitrios Papadouris; Kenneth S Rholl; John B Smirniotopoulos; Arina van Breda Journal: J Vasc Interv Radiol Date: 2013-10-28 Impact factor: 3.464
Authors: Jafar Golzarian; Alberto A Antunes; Tiago Bilhim; Francisco Cesar Carnevale; Badrinath Konety; Kevin T McVary; J Kellogg Parsons; João-Martins Pisco; David N Siegel; James Spies; Neil Wasserman; Naveen Gowda; Kamran Ahrar Journal: J Vasc Interv Radiol Date: 2014-02-21 Impact factor: 3.464
Authors: David Bonekamp; Michael A Jacobs; Riham El-Khouli; Dan Stoianovici; Katarzyna J Macura Journal: Radiographics Date: 2011 May-Jun Impact factor: 5.333
Authors: Hong Truong; Jennifer Logan; Baris Turkbey; M Minhaj Siddiqui; Soroush Rais-Bahrami; Anthony N Hoang; Chad Pusateri; Brian Shuch; Annerleim Walton-Diaz; Srinivas Vourganti; Jeffrey Nix; Lambros Stamatakis; Colette Harris; Celene Chua; Peter L Choyke; Bradford J Wood; Peter A Pinto Journal: Can J Urol Date: 2013-12 Impact factor: 1.344
Authors: Tiago Bilhim; João Pisco; Hugo Rio Tinto; Lúcia Fernandes; Luís Campos Pinheiro; Marisa Duarte; José A Pereira; António G Oliveira; João O'Neill Journal: Cardiovasc Intervent Radiol Date: 2012-12-12 Impact factor: 2.740
Authors: Vanesa Lucas-Cava; Francisco Miguel Sánchez-Margallo; Virginio García-Martínez; Carmen López-Sánchez; Claudia Báez-Díaz; Luis Dávila-Gómez; Juan Rafael Lima-Rodríguez; Fei Sun Journal: Transl Androl Urol Date: 2021-02
Authors: Vanessa F Schmidt; Mirjam Schirren; Maurice M Heimer; Philipp M Kazmierczak; Clemens C Cyran; Moritz Wildgruber; Max Seidensticker; Jens Ricke; Olga Solyanik Journal: Diagnostics (Basel) Date: 2022-02-25