BACKGROUND: Cryolipolysis received U.S. Food and Drug Administration clearance for reducing fat from the flanks, abdomen, and thighs. The upper arms are an off-label indication for cryolipolysis, and outcome data on reducing fat from the arms using a cryolipolytic device has rarely been published. OBJECTIVE: This pilot study evaluated cryolipolysis to reduce upper arm fat. MATERIALS AND METHODS: A flat vacuum applicator was used to treat seven subjects in a single-side study. The patients underwent one cycle of upper-arm cryolipolysis treatment, and the contralateral arm served as a control. Follow-up was conducted at 8 weeks. Equalization treatments were delivered subsequently to the opposite arm. Efficacy was evaluated by ultrasound imaging, physician's assessment, and patient satisfaction. Side effects and adverse events were monitored. RESULTS: Ultrasound measurements showed a decrease in the fat layer at 83.3% of the 12 measured sites. The mean reduction in fat layer thickness was 15.3%, corresponding to 2.03 mm. A significant difference was detected between baseline and 8-week assessments (p = 0.001). CONCLUSION: One treatment using a flat vacuum cryolipolysis applicator was safe and effective to reduce arm fat.
BACKGROUND: Cryolipolysis received U.S. Food and Drug Administration clearance for reducing fat from the flanks, abdomen, and thighs. The upper arms are an off-label indication for cryolipolysis, and outcome data on reducing fat from the arms using a cryolipolytic device has rarely been published. OBJECTIVE: This pilot study evaluated cryolipolysis to reduce upper arm fat. MATERIALS AND METHODS: A flat vacuum applicator was used to treat seven subjects in a single-side study. The patients underwent one cycle of upper-arm cryolipolysis treatment, and the contralateral arm served as a control. Follow-up was conducted at 8 weeks. Equalization treatments were delivered subsequently to the opposite arm. Efficacy was evaluated by ultrasound imaging, physician's assessment, and patient satisfaction. Side effects and adverse events were monitored. RESULTS: Ultrasound measurements showed a decrease in the fat layer at 83.3% of the 12 measured sites. The mean reduction in fat layer thickness was 15.3%, corresponding to 2.03 mm. A significant difference was detected between baseline and 8-week assessments (p = 0.001). CONCLUSION: One treatment using a flat vacuum cryolipolysis applicator was safe and effective to reduce arm fat.
Authors: Suzanne L Kilmer; Sue Ellen Cox; Brian D Zelickson; Eric P Bachelor; Sylvia Gamio; Rafael Ostrowski; Linda D Pham; W Grant Stevens Journal: Dermatol Surg Date: 2020-10 Impact factor: 2.914