Literature DB >> 26733617

Management of atrial fibrillation in patients with chronic kidney disease in Europe Results of the European Heart Rhythm Association Survey.

Tatjana S Potpara1, Radoslaw Lenarczyk2, Torben B Larsen3, Jean-Claude Deharo4, Jian Chen5, Nikolaos Dagres6.   

Abstract

The purpose of this European Heart Rhythm (EHRA) Scientific Initiatives Committee EP Wire Survey was to assess 'real-world' practice in the management of patients with atrial fibrillation (AF) and chronic kidney disease (CKD) in the European Eelectrophysiology centres. Of 41 responding centres, 39 (95.1%) and 37 (90.2%) routinely evaluated renal function in AF patients at first presentation and during follow-up, respectively, but 13 centres (31.7%) re-assessed advanced CKD only at ≥1-year intervals. While the use of oral anticoagulants (OACs) in mild-to-moderate CKD patients was mostly guided by individual patient stroke risk, 31% of the centres used no therapy, or aspirin or the left appendage occlusion in patients with advanced CKD and HAS-BLED ≥ 3. Vitamin K antagonists (VKAs) were preferred in patients with severe CKD or under renal replacement therapy (RRT), any non-VKA in patients with mild CKD, and apixaban in patients with moderate CKD. Rhythm control was preferred in patients with mild-to-moderate CKD (48.7% of centres), and rate control in patients with severe CKD (51.2% of centres). In 20 centres (48.8%), AF ablation was not performed in advanced CKD patients. Most centres performed AF ablation on OAC, but heparin bridging was still used in >10% of centres. Our survey has shown that the importance of renal function monitoring in AF patients is well recognized in clinical practice. In patients with mild-to-moderate CKD, AF is mostly managed according to the guideline recommendations, but more data are needed to guide the management of AF in patients with severe CKD or RRT. Published on behalf of the European Society of Cardiology. All rights reserved.
© The Author 2015. For permissions please email: journals.permissions@oup.com.

Entities:  

Keywords:  Anticoagulation; Atrial fibrillation; Chronic kidney disease; EHRA survey; EP wire; Management of atrial fibrillation; Non-vitamin K oral anticoagulants; Renal replacement therapy; Stroke prevention; Vitamin K antagonists

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Year:  2015        PMID: 26733617     DOI: 10.1093/europace/euv416

Source DB:  PubMed          Journal:  Europace        ISSN: 1099-5129            Impact factor:   5.214


  5 in total

Review 1.  Use of oral anticoagulants in patients with atrial fibrillation and renal dysfunction.

Authors:  Tatjana S Potpara; Charles J Ferro; Gregory Y H Lip
Journal:  Nat Rev Nephrol       Date:  2018-03-26       Impact factor: 28.314

2.  Treatment implications of renal disease in patients with atrial fibrillation: The BALKAN-AF survey.

Authors:  Monika Kozieł; Stefan Simovic; Nikola Pavlovic; Milan Nedeljkovic; Aleksandar Kocijancic; Vilma Paparisto; Ljilja Music; Elina Trendafilova; Anca Rodica Dan; Sime Manola; Zumreta Kusljugic; Gheorghe-Andrei Dan; Gregory Y H Lip; Tatjana S Potpara
Journal:  J Arrhythm       Date:  2020-07-19

Review 3.  Direct oral anticoagulants in patients with chronic kidney disease: patient selection and special considerations.

Authors:  Jens Lutz; Kerstin Jurk; Helmut Schinzel
Journal:  Int J Nephrol Renovasc Dis       Date:  2017-06-12

Review 4.  Anticoagulation in chronic kidney disease: from guidelines to clinical practice.

Authors:  Viviana Aursulesei; Irina Iuliana Costache
Journal:  Clin Cardiol       Date:  2019-05-28       Impact factor: 2.882

5.  Chronic Kidney Disease, Time in Therapeutic Range and Adverse Clinical Outcomes in Anticoagulated Patients with Non-valvular Atrial Fibrillation: Observations from the SPORTIF Trials.

Authors:  Marco Proietti; Deirdre A Lane; Gregory Y H Lip
Journal:  EBioMedicine       Date:  2016-04-19       Impact factor: 8.143

  5 in total

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