| Literature DB >> 26733617 |
Tatjana S Potpara1, Radoslaw Lenarczyk2, Torben B Larsen3, Jean-Claude Deharo4, Jian Chen5, Nikolaos Dagres6.
Abstract
The purpose of this European Heart Rhythm (EHRA) Scientific Initiatives Committee EP Wire Survey was to assess 'real-world' practice in the management of patients with atrial fibrillation (AF) and chronic kidney disease (CKD) in the European Eelectrophysiology centres. Of 41 responding centres, 39 (95.1%) and 37 (90.2%) routinely evaluated renal function in AF patients at first presentation and during follow-up, respectively, but 13 centres (31.7%) re-assessed advanced CKD only at ≥1-year intervals. While the use of oral anticoagulants (OACs) in mild-to-moderate CKD patients was mostly guided by individual patient stroke risk, 31% of the centres used no therapy, or aspirin or the left appendage occlusion in patients with advanced CKD and HAS-BLED ≥ 3. Vitamin K antagonists (VKAs) were preferred in patients with severe CKD or under renal replacement therapy (RRT), any non-VKA in patients with mild CKD, and apixaban in patients with moderate CKD. Rhythm control was preferred in patients with mild-to-moderate CKD (48.7% of centres), and rate control in patients with severe CKD (51.2% of centres). In 20 centres (48.8%), AF ablation was not performed in advanced CKD patients. Most centres performed AF ablation on OAC, but heparin bridging was still used in >10% of centres. Our survey has shown that the importance of renal function monitoring in AF patients is well recognized in clinical practice. In patients with mild-to-moderate CKD, AF is mostly managed according to the guideline recommendations, but more data are needed to guide the management of AF in patients with severe CKD or RRT. Published on behalf of the European Society of Cardiology. All rights reserved.Entities:
Keywords: Anticoagulation; Atrial fibrillation; Chronic kidney disease; EHRA survey; EP wire; Management of atrial fibrillation; Non-vitamin K oral anticoagulants; Renal replacement therapy; Stroke prevention; Vitamin K antagonists
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Year: 2015 PMID: 26733617 DOI: 10.1093/europace/euv416
Source DB: PubMed Journal: Europace ISSN: 1099-5129 Impact factor: 5.214