| Literature DB >> 26728742 |
D A Faizullin1, Yu F Zuev2, L Ya Zakharova3, A G Pokrovsky4, V A Korobeinikov4, T A Mukhametzyanov5, A I Konovalov3.
Abstract
The internal structure of DNA lipoplexes with hydroxyethylated alkylammonium gemini surfactants (GS) with high transfection activity was studied by circular dichroism. It was shown that the efficiency of transfection of HEK293T cells with the pEGFP-N1 circular plasmid was different from zero only in the region of existence of chiral supramolecular DNA-GS complexes and reaches a maximum at concentrations at which the spontaneous aggregation of components is observed.Entities:
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Year: 2016 PMID： 26728742 DOI： 10.1134/S1607672915060204
Source DB: PubMed Journal: Dokl Biochem Biophys ISSN： 1607-6729 Impact factor: 0.788