Literature DB >> 26726291

Insights into acute myeloid leukemia via single cell network profiling.

Steven M Kornblau1, Mark D Minden2, Donna Hogge3, AileenC Cohen4, Alessandra Cesano5.   

Abstract

Single Cell Network Profiling (SCNP) uses multi-parameter flow cytometry to simultaneously measure resting and evoked intracellular signalling molecules and pathways in distinct cell subsets within a complex tissue sample. This review focuses on the utility of SCNP and its potential applications for chemotherapy selection in Acute Myeloid Leukemia (AML).

Entities:  

Year:  2010        PMID： 26726291      PMCID： PMC4696776     

Source DB:  PubMed          Journal:  Clin Lab Int        ISSN： 1373-1580


  11 in total

1.  Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell.

Authors:  D Bonnet; J E Dick
Journal:  Nat Med       Date:  1997-07       Impact factor: 53.440

2.  Age and acute myeloid leukemia.

Authors:  Frederick R Appelbaum; Holly Gundacker; David R Head; Marilyn L Slovak; Cheryl L Willman; John E Godwin; Jeanne E Anderson; Stephen H Petersdorf
Journal:  Blood       Date:  2006-02-02       Impact factor: 22.113

3.  Long-term follow-up of Cancer and Leukemia Group B studies in acute myeloid leukemia.

Authors:  C A Schiffer; R Dodge; R A Larson
Journal:  Cancer       Date:  1997-12-01       Impact factor: 6.860

4.  Long-term survival in acute myeloid leukemia: the Eastern Cooperative Oncology Group experience.

Authors:  J M Bennett; M L Young; J W Andersen; P A Cassileth; M S Tallman; E Paietta; P H Wiernik; J M Rowe
Journal:  Cancer       Date:  1997-12-01       Impact factor: 6.860

Review 5.  Drug therapy for acute myeloid leukemia.

Authors:  Martin S Tallman; D Gary Gilliland; Jacob M Rowe
Journal:  Blood       Date:  2005-05-03       Impact factor: 22.113

6.  Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia.

Authors:  Richard F Schlenk; Konstanze Döhner; Jürgen Krauter; Stefan Fröhling; Andrea Corbacioglu; Lars Bullinger; Marianne Habdank; Daniela Späth; Michael Morgan; Axel Benner; Brigitte Schlegelberger; Gerhard Heil; Arnold Ganser; Hartmut Döhner
Journal:  N Engl J Med       Date:  2008-05-01       Impact factor: 91.245

7.  Single cell profiling of potentiated phospho-protein networks in cancer cells.

Authors:  Jonathan M Irish; Randi Hovland; Peter O Krutzik; Omar D Perez; Øystein Bruserud; Bjørn T Gjertsen; Garry P Nolan
Journal:  Cell       Date:  2004-07-23       Impact factor: 41.582

Review 8.  Patient-specific classifications of human malignant disease.

Authors:  David R Parkinson; Alessandra Cesano
Journal:  Curr Opin Mol Ther       Date:  2009-06

9.  Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates.

Authors:  Nikesh Kotecha; Nikki J Flores; Jonathan M Irish; Erin F Simonds; Debbie S Sakai; Sophie Archambeault; Ernesto Diaz-Flores; Marc Coram; Kevin M Shannon; Garry P Nolan; Mignon L Loh
Journal:  Cancer Cell       Date:  2008-10-07       Impact factor: 31.743

Review 10.  Molecular signatures in acute myeloid leukemia.

Authors:  Krzysztof Mrózek; Michael D Radmacher; Clara D Bloomfield; Guido Marcucci
Journal:  Curr Opin Hematol       Date:  2009-03       Impact factor: 3.284
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