Literature DB >> 26721494

Characterization of Circular RNAs.

Yang Zhang1, Li Yang2, Ling-Ling Chen3,4.   

Abstract

Accumulated lines of evidence reveal that a large number of circular RNAs are produced in transcriptomes from fruit fly to mouse and human. Unlike linear RNAs shaped with 5' cap and 3' tail, circular RNAs are characterized by covalently closed loop structures without open terminals, thus requiring specific treatments for their identification and validation. Here, we describe a detailed pipeline for the characterization of circular RNAs. It has been successfully applied to the study of circular intronic RNAs derived from intron lariats (ciRNAs) and circular RNAs produced from back spliced exons (circRNAs) in human.

Entities:  

Keywords:  Circular RNAs; RNA fractionation; RNase R; ciRNAs; circRNAs

Mesh：

Substances：

Year:  2016        PMID： 26721494     DOI： 10.1007/978-1-4939-3378-5_17

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  14 in total

Review 1.  The expanding regulatory mechanisms and cellular functions of circular RNAs.

Authors:  Ling-Ling Chen
Journal:  Nat Rev Mol Cell Biol       Date:  2020-05-04       Impact factor: 94.444

Review 2.  Circular RNAs in cardiovascular diseases.

Authors:  Xiaohan Mei; Shi-You Chen
Journal:  Pharmacol Ther       Date:  2021-09-27       Impact factor: 12.310

3.  Circular RNA migration in agarose gel electrophoresis.

Authors:  Brian T Abe; R Alexander Wesselhoeft; Robert Chen; Daniel G Anderson; Howard Y Chang
Journal:  Mol Cell       Date:  2022-03-30       Impact factor: 19.328

Review 4.  Best practices to ensure robust investigation of circular RNAs: pitfalls and tips.

Authors:  Samantha Dodbele; Nebibe Mutlu; Jeremy E Wilusz
Journal:  EMBO Rep       Date:  2021-02-25       Impact factor: 8.807

5.  Comprehensive Identification of Translatable Circular RNAs Using Polysome Profiling.

Authors:  Yanwen Ye; Zefeng Wang; Yun Yang
Journal:  Bio Protoc       Date:  2021-09-20

6.  Deficiency in the Ubiquitin Conjugating Enzyme UBE2A in Alzheimer's Disease (AD) is Linked to Deficits in a Natural Circular miRNA-7 Sponge (circRNA; ciRS-7).

Authors:  Yuhai Zhao; Peter N Alexandrov; Vivian Jaber; Walter J Lukiw
Journal:  Genes (Basel)       Date:  2016-12-05       Impact factor: 4.096

7.  Circular RNA expression profiling of human granulosa cells during maternal aging reveals novel transcripts associated with assisted reproductive technology outcomes.

Authors:  Jing Cheng; Jia Huang; Suzhen Yuan; Su Zhou; Wei Yan; Wei Shen; Yun Chen; Xi Xia; Aiyue Luo; Da Zhu; Shixuan Wang
Journal:  PLoS One       Date:  2017-06-23       Impact factor: 3.240

8.  Identification and characterization of a novel Epstein-Barr Virus-encoded circular RNA from LMP-2 Gene.

Authors:  Ke-En Tan; Wei Lun Ng; Georgi K Marinov; Ken Hung-On Yu; Lu Ping Tan; Ee Shan Liau; Sook Yan Goh; Kok Siong Yeo; Kevin Y Yip; Kwok-Wai Lo; Alan Soo-Beng Khoo; Lee-Fah Yap; Chee-Kwee Ea; Yat-Yuen Lim
Journal:  Sci Rep       Date:  2021-07-13       Impact factor: 4.379

Review 9.  The Nefarious Nexus of Noncoding RNAs in Cancer.

Authors:  Eleni Anastasiadou; Alberto Faggioni; Pankaj Trivedi; Frank J Slack
Journal:  Int J Mol Sci       Date:  2018-07-17       Impact factor: 5.923

10.  A novel plasma circular RNA circFARSA is a potential biomarker for non-small cell lung cancer.

Authors:  Dong Hang; Jing Zhou; Na Qin; Wen Zhou; Hongxia Ma; Guangfu Jin; Zhibin Hu; Juncheng Dai; Hongbing Shen
Journal:  Cancer Med       Date:  2018-05-02       Impact factor: 4.452
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