| Literature DB >> 26720877 |
Andrew E Heidari1, Samer Moghaddam2, Kimberly K Truong, Kimberly K Troung2, Lidek Chou3, Carl Genberg4, Matthew Brenner5, Zhongping Chen1.
Abstract
Biofilm formation has been linked to ventilator-associated pneumonia, which is a prevalent infection in hospital intensive care units. Currently, there is no rapid diagnostic tool to assess the degree of biofilm formation or cellular biofilm composition. Optical coherence tomography (OCT) is a minimally invasive, nonionizing imaging modality that can be used to provide high-resolution cross-sectional images. Biofilm deposited in critical care patients’ endotracheal tubes was analyzed in vitro. This study demonstrates that OCT could potentially be used as a diagnostic tool to analyze and assess the degree of biofilm formation and extent of airway obstruction caused by biofilm in endotracheal tubes.Entities:
Mesh:
Year: 2015 PMID: 26720877 PMCID: PMC4686586 DOI: 10.1117/1.JBO.20.12.126010
Source DB: PubMed Journal: J Biomed Opt ISSN: 1083-3668 Impact factor: 3.170