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Literature DB >> 26718212

Long non-coding RNAs: emerging players in osteosarcoma.

Abstract

Osteosarcoma is the most common kind of primary bone tumors with high morbidity in infants and adolescents. While the molecular mechanism of osteosarcoma has gained considerable attention, the mechanisms underlying its initiation and progression remain unclear. Recent studies have discovered that long non-coding RNAs (lncRNAs) play an important role in multiply biological processes including cell development, differentiation, proliferation, invasion, and migration. Deregulated expression of lncRNAs has been found in cancers including osteosarcoma. This review summarized the deregulation and functional role of lncRNAs in osteosarcoma and their potential application for diagnosis and treatment of osteosarcoma.

Entities: Disease Species

Keywords: Long non-coding RNAs; MALAT1; Osteosarcoma; lncRNAs

Mesh：

Substances：

Year: 2015 PMID： 26718212 DOI： 10.1007/s13277-015-4749-4

Source DB: PubMed Journal: Tumour Biol ISSN： 1010-4283

69 in total

1. The role of MALAT1/miR-1/slug axis on radioresistance in nasopharyngeal carcinoma.

Authors: Chuan Jin; Bingchuan Yan; Qin Lu; Yanmin Lin; Lei Ma
Journal: Tumour Biol Date: 2015-10-20

2. Changes in genomic imprinting and gene expression associated with transformation in a model of human osteosarcoma.

Authors: Yi Li; Gang Meng; Qiao-nan Guo
Journal: Exp Mol Pathol Date: 2008-04-16 Impact factor: 3.362

3. miR-16 inhibits cell proliferation by targeting IGF1R and the Raf1-MEK1/2-ERK1/2 pathway in osteosarcoma.

Authors: Lei Chen; Qing Wang; Guo-dong Wang; Hua-song Wang; Yong Huang; Xi-ming Liu; Xian-hua Cai
Journal: FEBS Lett Date: 2013-03-15 Impact factor: 4.124

4. Low miR-34a and miR-192 are associated with unfavorable prognosis in patients suffering from osteosarcoma.

Authors: Yuan Wang; Lian-Shun Jia; Wen Yuan; Zhao Wu; Hai-Bo Wang; Tao Xu; Jing-Chuan Sun; Ke-Fu Cheng; Jian-Gang Shi
Journal: Am J Transl Res Date: 2015-01-15 Impact factor: 4.060

5. Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway.

Authors: Guohui Wan; Rohit Mathur; Xiaoxiao Hu; Yunhua Liu; Xinna Zhang; Guang Peng; Xiongbin Lu
Journal: Cell Signal Date: 2013-02-14 Impact factor: 4.315

6. MALAT1 promotes the proliferation and metastasis of osteosarcoma cells by activating the PI3K/Akt pathway.

Authors: Yongqiang Dong; Guojun Liang; Bo Yuan; Chaoqun Yang; Rui Gao; Xuhui Zhou
Journal: Tumour Biol Date: 2014-11-28

7. Expression of long non-coding RNA LOC285194 and its prognostic significance in human pancreatic ductal adenocarcinoma.

Authors: Yue-Chao Ding; Wei Yu; Chao Ma; Qian Wang; Chang-Shan Huang; Tao Huang
Journal: Int J Clin Exp Pathol Date: 2014-10-15

8. A novel long non-coding RNA, hypoxia-inducible factor-2α promoter upstream transcript, functions as an inhibitor of osteosarcoma stem cells in vitro.

Authors: Yongcheng Wang; Jie Yao; Haoye Meng; Zhiguo Yu; Zhigang Wang; Xueling Yuan; Hong Chen; Aiyuan Wang
Journal: Mol Med Rep Date: 2014-12-01 Impact factor: 2.952

9. Long noncoding RNA ANRIL indicates a poor prognosis of gastric cancer and promotes tumor growth by epigenetically silencing of miR-99a/miR-449a.

Authors: Er-bao Zhang; Rong Kong; Dan-dan Yin; Liang-hui You; Ming Sun; Liang Han; Tong-peng Xu; Rui Xia; Jin-song Yang; Wei De; Jin fei Chen
Journal: Oncotarget Date: 2014-04-30

10. Plasma level of metastasis-associated lung adenocarcinoma transcript 1 is associated with liver damage and predicts development of hepatocellular carcinoma.

Authors: Hirotaka Konishi; Daisuke Ichikawa; Yusuke Yamamoto; Tomohiro Arita; Katsutoshi Shoda; Hidekazu Hiramoto; Junichi Hamada; Hiroshi Itoh; Yuji Fujita; Shuhei Komatsu; Atsushi Shiozaki; Hisashi Ikoma; Toshiya Ochiai; Eigo Otsuji
Journal: Cancer Sci Date: 2016-02-09 Impact factor: 6.716

44 in total

1. LncRNA ODRUL Contributes to Osteosarcoma Progression through the miR-3182/MMP2 Axis.

Authors: Kun-Peng Zhu; Xiao-Long Ma; Chun-Lin Zhang
Journal: Mol Ther Date: 2017-07-05 Impact factor: 11.454

2. Circulating microRNA signature of steroid-induced osteonecrosis of the femoral head.

Authors: Zheng Li; Chao Jiang; Xingye Li; William K K Wu; Xi Chen; Shibai Zhu; Chanhua Ye; Matthew T V Chan; Wenwei Qian
Journal: Cell Prolif Date: 2017-12-04 Impact factor: 6.831

3. LINC00994 promoted invasion and proliferation of gastric cancer cell via regulating miR-765-3p.

Authors: Ling Yuan; Tingting Ma; Wenjing Liu; Yan Chen; Qihui Yuan; Mengyi Ye; Lei Yu; Jiaxin Li; Yang Niu; Yi Nan
Journal: Am J Transl Res Date: 2019-10-15 Impact factor: 4.060

Review 4. NEAT1: A novel cancer-related long non-coding RNA.

Authors: Xin Yu; Zheng Li; Heyi Zheng; Matthew T V Chan; William Ka Kei Wu
Journal: Cell Prolif Date: 2017-01-19 Impact factor: 6.831

5. MicroRNA-665 suppressed the invasion and metastasis of osteosarcoma by directly inhibiting RAB23.

Authors: Chenhui Dong; Quanyin Du; Zimin Wang; Yu Wang; Siyu Wu; Aimin Wang
Journal: Am J Transl Res Date: 2016-11-15 Impact factor: 4.060

Review 6. Molecular genetics of osteosarcoma.

Authors: Kirby Rickel; Fang Fang; Jianning Tao
Journal: Bone Date: 2016-10-17 Impact factor: 4.398

7. Long non-coding RNA AK093407 promotes proliferation and inhibits apoptosis of human osteosarcoma cells via STAT3 activation.

Authors: Yongkun Wang; Tingting Liang; Yao Wang; Yan Huang; Ye Li
Journal: Am J Cancer Res Date: 2017-04-01 Impact factor: 6.166