Literature DB >> 26713777

Lymph node retrieval for colorectal cancer: Estimation of the minimum resection length to achieve at least 12 lymph nodes for the pathological analysis.

Gianpiero Gravante1, Rupert Parker1, Mohamed Elshaer2, Adimabua Christopher Mogekwu1, Nada Humayun1, Katie Thomas1, Rachael Thomson1, Sarah Hudson1, Roberto Sorge3, Katy Gardiner1, Salem Al-Hamali1, Mohamed Rashed1, Ashish Kelkar1, Saleem El-Rabaa1.   

Abstract

INTRODUCTION: Adequate lymph node retrieval is important in colorectal cancer staging for the selection of patients that necessitate adjuvant treatments. The minimum number of 12 lymph nodes is one of the premises and is dependent, among the other factors, from the length of bowel resected. We have reviewed our specimens to identify the high-risk operations for inadequate nodal sampling and estimate the minimum length of bowel needed to resect to achieve this purpose.
MATERIALS AND METHODS: A retrospective review of colorectal specimens over 10 years of activity looking at data including location of the tumor, type of operation performed, length of bowel resected and number of lymph nodes retrieved.
RESULTS: Abdominoperineal and Hartmann's resections produced significant lower adequate retrievals compared to other colorectal operations, corresponding to 45.4% and 59.1% of cases respectively. The measured average length of bowel was 30 cm and 25 cm respectively, increasing the length to 36 cm and 42 cm would increase the adequacy rate to 90%.
CONCLUSIONS: Abdominoperineal and Hartmann's resections are, in our series, high-risk operations that frequently do not produce the minimum number of lymph nodes necessary. These operations may require additional maneuvers such as mobilization of the splenic flexure to achieve the minimum length of bowel to resect.
Copyright © 2015 IJS Publishing Group Limited. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Abdominoperineal resection; Colorectal cancer; Hartmann resection; Lymph node; Staging

Mesh:

Year:  2015        PMID: 26713777     DOI: 10.1016/j.ijsu.2015.12.062

Source DB:  PubMed          Journal:  Int J Surg        ISSN: 1743-9159            Impact factor:   6.071


  5 in total

1.  Comparative survival risks in patients undergoing abdominoperineal resection and sphincter-saving operation for rectal cancer: a 10-year cohort analysis using propensity score matching.

Authors:  Hyun Gu Lee; Chan Wook Kim; Jong Lyul Lee; Yong Sik Yoon; In Ja Park; Seok-Byung Lim; Chang Sik Yu; Jin Cheon Kim
Journal:  Int J Colorectal Dis       Date:  2022-04-05       Impact factor: 2.571

2.  Should there be a specific length of the colon-rectum segment to be resected for an adequate number of lymph nodes in cases of colorectal cancers? A retrospective multi-center study.

Authors:  Orhan Üreyen; Cemal Ulusoy; Atahan Acar; Fazıl Sağlam; İlker Kızıloğlu; Ali Alemdar; Kemal Murat Atahan; Emrah Dadalı; Serkan Karaisli; Mehmet Can Aydın; Enver İlhan; Hakan Güven
Journal:  Turk J Surg       Date:  2020-03-18

3.  Lymph node retrieval in colorectal cancer: determining factors and prognostic significance.

Authors:  Johannes Betge; Lars Harbaum; Marion J Pollheimer; Richard A Lindtner; Peter Kornprat; Matthias P Ebert; Cord Langner
Journal:  Int J Colorectal Dis       Date:  2017-02-16       Impact factor: 2.571

4.  Can Ex Vivo Magnetic Resonance Imaging of Rectal Cancer Specimens Improve the Mesorectal Lymph Node Yield for Pathological Examination?

Authors:  Rutger Stijns; Bart Philips; Carla Wauters; Johannes de Wilt; Iris Nagtegaal; Tom Scheenen
Journal:  Invest Radiol       Date:  2019-10       Impact factor: 6.016

Review 5.  Application of Carbon Nanoparticles in Tracing Lymph Nodes and Locating Tumors in Colorectal Cancer: A Concise Review.

Authors:  Pengcheng Liu; Jie Tan; Qiuwen Tan; Li Xu; Tao He; Qing Lv
Journal:  Int J Nanomedicine       Date:  2020-12-02
  5 in total

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