Literature DB >> 2671370

DNA and associated targets for drug design.

L H Hurley1.   

Abstract

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Year:  1989        PMID： 2671370     DOI： 10.1021/jm00129a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  17 in total

1.  Allosteric, chiral-selective drug binding to DNA.

Authors:  X Qu; J O Trent; I Fokt; W Priebe; J B Chaires
Journal:  Proc Natl Acad Sci U S A       Date:  2000-10-24       Impact factor: 11.205

2.  Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription.

Authors:  Adam Siddiqui-Jain; Cory L Grand; David J Bearss; Laurence H Hurley
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-23       Impact factor: 11.205

3.  Controlling nucleic acid secondary structure by intercalation: effects of DNA strand length on coralyne-driven duplex disproportionation.

Authors:  Swapan S Jain; Matjaz Polak; Nicholas V Hud
Journal:  Nucleic Acids Res       Date:  2003-08-01       Impact factor: 16.971

4.  Noncovalent DNA binding drives DNA alkylation by leinamycin: evidence that the Z,E-5-(thiazol-4-yl)-penta-2,4-dienone moiety of the natural product serves as an atypical DNA intercalator.

Authors:  Mostafa I Fekry; Jozsef Szekely; Sanjay Dutta; Leonid Breydo; Hong Zang; Kent S Gates
Journal:  J Am Chem Soc       Date:  2011-10-18       Impact factor: 15.419

Review 5.  Transcription factor AP-2 and monoaminergic functions in the central nervous system.

Authors:  M Damberg
Journal:  J Neural Transm (Vienna)       Date:  2005-06-15       Impact factor: 3.575

6.  Finding potential DNA-binding compounds by using molecular shape.

Authors:  P D Grootenhuis; D C Roe; P A Kollman; I D Kuntz
Journal:  J Comput Aided Mol Des       Date:  1994-12       Impact factor: 3.686

Review 7.  Mechanism of DNA-drug interactions.

Authors:  P Prabhakar; A M Kayastha
Journal:  Appl Biochem Biotechnol       Date:  1994-04       Impact factor: 2.926

8.  Targeting MYC Expression through G-Quadruplexes.

Authors:  Tracy A Brooks; Laurence H Hurley
Journal:  Genes Cancer       Date:  2010-06

Review 9.  The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics.

Authors:  Tracy A Brooks; Laurence H Hurley
Journal:  Nat Rev Cancer       Date:  2009-11-12       Impact factor: 60.716

10.  Kedarcidin chromophore: an enediyne that cleaves DNA in a sequence-specific manner.

Authors:  N Zein; K L Colson; J E Leet; D R Schroeder; W Solomon; T W Doyle; A M Casazza
Journal:  Proc Natl Acad Sci U S A       Date:  1993-04-01       Impact factor: 11.205
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