Literature DB >> 26713276

Conflicts of interest in nutritional sciences: The forgotten bias in meta-analysis.

Michel Lucas1.   

Abstract

Awareness of conflicts of interest (COI) in medicine began in the 1980s. More recently, the problem has gained notoriety in nutritional sciences. COI with industry could bias study conclusions in the context of research activities and scientific publications on nutritional sciences. The issue of COI in nutritional sciences deserves more attention and requires careful analyses as biased information can negatively impact the development of dietary guidelines and, ultimately, population health. Decision-making is generally based on available, published evidence, but when the results are ambivalent, it is easier to opt for the status quo and ask for more studies. Readers might wonder if research is subsidized by industry as a counterbalancing strategy based on levels of evidence-only to slow down eminent positions and/or legislation on the food sector? How can this problem be overcome without producing paranoia and McCarthyism while trying to be as methodological as possible?

Entities:  

Keywords:  Bias; Conflicts of interest; Meta-analysis; Nutrition; Nutritional sciences; Systematic reviews

Year:  2015        PMID: 26713276      PMCID: PMC4686413          DOI: 10.5662/wjm.v5.i4.175

Source DB:  PubMed          Journal:  World J Methodol        ISSN: 2222-0682


  24 in total

1.  Asymmetric funnel plots and publication bias in meta-analyses of diagnostic accuracy.

Authors:  Fujian Song; Khalid S Khan; Jacqueline Dinnes; Alex J Sutton
Journal:  Int J Epidemiol       Date:  2002-02       Impact factor: 7.196

Review 2.  Scope and impact of financial conflicts of interest in biomedical research: a systematic review.

Authors:  Justin E Bekelman; Yan Li; Cary P Gross
Journal:  JAMA       Date:  2003 Jan 22-29       Impact factor: 56.272

3.  Understanding bias--the case for careful study.

Authors:  Lisa Rosenbaum
Journal:  N Engl J Med       Date:  2015-05-14       Impact factor: 91.245

4.  Understanding financial conflicts of interest.

Authors:  D F Thompson
Journal:  N Engl J Med       Date:  1993-08-19       Impact factor: 91.245

5.  The perils of ignoring history: Big Tobacco played dirty and millions died. How similar is Big Food?

Authors:  Kelly D Brownell; Kenneth E Warner
Journal:  Milbank Q       Date:  2009-03       Impact factor: 4.911

6.  Environmental tobacco smoke. The Brown and Williamson documents.

Authors:  D E Barnes; P Hanauer; J Slade; L A Bero; S A Glantz
Journal:  JAMA       Date:  1995-07-19       Impact factor: 56.272

7.  Selective publication of antidepressant trials and its influence on apparent efficacy.

Authors:  Erick H Turner; Annette M Matthews; Eftihia Linardatos; Robert A Tell; Robert Rosenthal
Journal:  N Engl J Med       Date:  2008-01-17       Impact factor: 91.245

8.  Relationship between funding source and conclusion among nutrition-related scientific articles.

Authors:  Lenard I Lesser; Cara B Ebbeling; Merrill Goozner; David Wypij; David S Ludwig
Journal:  PLoS Med       Date:  2007-01       Impact factor: 11.069

9.  Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.

Authors:  David Moher; Alessandro Liberati; Jennifer Tetzlaff; Douglas G Altman
Journal:  BMJ       Date:  2009-07-21

Review 10.  Antidepressant efficacy of agomelatine: meta-analysis of published and unpublished studies.

Authors:  David Taylor; Anna Sparshatt; Seema Varma; Olubanke Olofinjana
Journal:  BMJ       Date:  2014-03-19
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  2 in total

1.  Perspective: NutriGrade: A Scoring System to Assess and Judge the Meta-Evidence of Randomized Controlled Trials and Cohort Studies in Nutrition Research.

Authors:  Lukas Schwingshackl; Sven Knüppel; Carolina Schwedhelm; Georg Hoffmann; Benjamin Missbach; Marta Stelmach-Mardas; Stefan Dietrich; Fabian Eichelmann; Evangelos Kontopantelis; Khalid Iqbal; Krasimira Aleksandrova; Stefan Lorkowski; Michael F Leitzmann; Anja Kroke; Heiner Boeing
Journal:  Adv Nutr       Date:  2016-11-15       Impact factor: 8.701

2.  What principles should guide interactions between population health researchers and the food industry? Systematic scoping review of peer-reviewed and grey literature.

Authors:  Katherine Cullerton; Jean Adams; Nita Forouhi; Oliver Francis; Martin White
Journal:  Obes Rev       Date:  2019-04-09       Impact factor: 9.213

  2 in total

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