Literature DB >> 26711015

The Role of Prostaglandin E(2) in Tumor-Associated Immunosuppression.

Dingzhi Wang1, Raymond N DuBois2.   

Abstract

Tumor-associated inflammation can create an immunosuppressive microenvironment allowing tumor cells to escape immunosurveillance. Inhibiting immunosuppression remains one of the major challenges in cancer immunotherapy via checkpoint inhibitors. Recent preclinical data from the Reis e Sousa group may provide a strong rationale for developing new therapeutics to subvert tumor-induced immunosuppression via prostaglandin inhibition.
Copyright © 2015 Elsevier Ltd. All rights reserved.

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Year:  2015        PMID： 26711015      PMCID： PMC4762482          DOI： 10.1016/j.molmed.2015.11.003

Source DB:  PubMed          Journal:  Trends Mol Med        ISSN： 1471-4914            Impact factor:   11.951


  10 in total

1.  Peroxisome proliferator-activated receptor δ promotes colonic inflammation and tumor growth.

Authors:  Dingzhi Wang; Lingchen Fu; Wei Ning; Lixia Guo; Xiaofei Sun; Sudhansu K Dey; Rupesh Chaturvedi; Keith T Wilson; Raymond N DuBois
Journal:  Proc Natl Acad Sci U S A       Date:  2014-04-24       Impact factor: 11.205

2.  Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy.

Authors:  Steven L Highfill; Yongzhi Cui; Amber J Giles; Jillian P Smith; Hua Zhang; Elizabeth Morse; Rosandra N Kaplan; Crystal L Mackall
Journal:  Sci Transl Med       Date:  2014-05-21       Impact factor: 17.956

Review 3.  Immunosuppression associated with chronic inflammation in the tumor microenvironment.

Authors:  Dingzhi Wang; Raymond N DuBois
Journal:  Carcinogenesis       Date:  2015-09-08       Impact factor: 4.944

Review 4.  Eicosanoids and cancer.

Authors:  Dingzhi Wang; Raymond N Dubois
Journal:  Nat Rev Cancer       Date:  2010-02-19       Impact factor: 60.716

Review 5.  Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung.

Authors:  R E Harris
Journal:  Inflammopharmacology       Date:  2009-04       Impact factor: 4.473

Review 6.  Checkpoint blocking antibodies in cancer immunotherapy.

Authors:  Chrisann Kyi; Michael A Postow
Journal:  FEBS Lett       Date:  2013-10-23       Impact factor: 4.124

Review 7.  An inflammatory mediator, prostaglandin E2, in colorectal cancer.

Authors:  Dingzhi Wang; Raymond N DuBois
Journal:  Cancer J       Date:  2013 Nov-Dec       Impact factor: 3.360

Review 8.  Inflammation and cancer: advances and new agents.

Authors:  Shanthini M Crusz; Frances R Balkwill
Journal:  Nat Rev Clin Oncol       Date:  2015-06-30       Impact factor: 66.675

9.  Prostaglandin E2 promotes intestinal tumor growth via DNA methylation.

Authors:  Dianren Xia; Dingzhi Wang; Sun-Hee Kim; Hiroshi Katoh; Raymond N DuBois
Journal:  Nat Med       Date:  2012-01-22       Impact factor: 53.440

10.  Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity.

Authors:  Santiago Zelenay; Annemarthe G van der Veen; Jan P Böttcher; Kathryn J Snelgrove; Neil Rogers; Sophie E Acton; Probir Chakravarty; Maria Romina Girotti; Richard Marais; Sergio A Quezada; Erik Sahai; Caetano Reis e Sousa
Journal:  Cell       Date:  2015-09-03       Impact factor: 41.582
  10 in total
  38 in total

1.  Aspirin Use and Colorectal Cancer Survival According to Tumor CD274 (Programmed Cell Death 1 Ligand 1) Expression Status.

Authors:  Tsuyoshi Hamada; Yin Cao; Zhi Rong Qian; Yohei Masugi; Jonathan A Nowak; Juhong Yang; Mingyang Song; Kosuke Mima; Keisuke Kosumi; Li Liu; Yan Shi; Annacarolina da Silva; Mancang Gu; Wanwan Li; NaNa Keum; Xuehong Zhang; Kana Wu; Jeffrey A Meyerhardt; Edward L Giovannucci; Marios Giannakis; Scott J Rodig; Gordon J Freeman; Daniel Nevo; Molin Wang; Andrew T Chan; Charles S Fuchs; Reiko Nishihara; Shuji Ogino
Journal:  J Clin Oncol       Date:  2017-04-13       Impact factor: 44.544

2.  Balancing the Checkpoint: Managing Colitis Associated with Dual Checkpoint Inhibitors and High-Dose Aspirin.

Authors:  Muhammad B Hammami; Ryan Gill; Nikhil Thiruvengadam; David Y Oh; Kendall Beck; Uma Mahadevan; Michael G Kattah
Journal:  Dig Dis Sci       Date:  2019-03       Impact factor: 3.199

3.  Metabolic remodeling contributes towards an immune-suppressive phenotype in glioblastoma.

Authors:  Pravin Kesarwani; Antony Prabhu; Shiva Kant; Prakash Chinnaiyan
Journal:  Cancer Immunol Immunother       Date:  2019-05-22       Impact factor: 6.968

4.  Prognostic association of PTGS2 (COX-2) over-expression according to BRAF mutation status in colorectal cancer: Results from two prospective cohorts and CALGB 89803 (Alliance) trial.

Authors:  Keisuke Kosumi; Tsuyoshi Hamada; Sui Zhang; Li Liu; Annacarolina da Silva; Hideo Koh; Tyler S Twombly; Kosuke Mima; Teppei Morikawa; Mingyang Song; Jonathan A Nowak; Reiko Nishihara; Leonard B Saltz; Donna Niedzwiecki; Fang-Shu Ou; Tyler Zemla; Robert J Mayer; Hideo Baba; Kimmie Ng; Marios Giannakis; Xuehong Zhang; Kana Wu; Edward L Giovannucci; Andrew T Chan; Charles S Fuchs; Jeffrey A Meyerhardt; Shuji Ogino
Journal:  Eur J Cancer       Date:  2019-03-01       Impact factor: 9.162

Review 5.  Insights into Pathogenic Interactions Among Environment, Host, and Tumor at the Crossroads of Molecular Pathology and Epidemiology.

Authors:  Shuji Ogino; Jonathan A Nowak; Tsuyoshi Hamada; Danny A Milner; Reiko Nishihara
Journal:  Annu Rev Pathol       Date:  2018-08-20       Impact factor: 23.472

Review 6.  The interplay between metabolic remodeling and immune regulation in glioblastoma.

Authors:  Pravin Kesarwani; Shiva Kant; Antony Prabhu; Prakash Chinnaiyan
Journal:  Neuro Oncol       Date:  2017-10-01       Impact factor: 12.300

Review 7.  Cyclooxygenase-2 in glioblastoma multiforme.

Authors:  Jiange Qiu; Zhi Shi; Jianxiong Jiang
Journal:  Drug Discov Today       Date:  2016-09-28       Impact factor: 7.851

8.  Prostaglandin E2 Induction Suppresses the Th1 Immune Responses in Cattle with Johne's Disease.

Authors:  Yamato Sajiki; Satoru Konnai; Tomohiro Okagawa; Asami Nishimori; Naoya Maekawa; Shinya Goto; Ryoyo Ikebuchi; Reiko Nagata; Satoko Kawaji; Yumiko Kagawa; Shinji Yamada; Yukinari Kato; Chie Nakajima; Yasuhiko Suzuki; Shiro Murata; Yasuyuki Mori; Kazuhiko Ohashi
Journal:  Infect Immun       Date:  2018-04-23       Impact factor: 3.441

Review 9.  Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion.

Authors:  José Pedro Friedmann Angeli; Dmitri V Krysko; Marcus Conrad
Journal:  Nat Rev Cancer       Date:  2019-07       Impact factor: 60.716

Review 10.  Endoplasmic reticulum stress signals in the tumour and its microenvironment.

Authors:  Xi Chen; Juan R Cubillos-Ruiz
Journal:  Nat Rev Cancer       Date:  2020-11-19       Impact factor: 60.716
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