Literature DB >> 20168319

Eicosanoids and cancer.

Dingzhi Wang1, Raymond N Dubois.   

Abstract

Eicosanoids, including prostaglandins and leukotrienes, are biologically active lipids that have been implicated in various pathological processes, such as inflammation and cancer. This Review highlights our understanding of the intricate roles of eicosanoids in epithelial-derived tumours and their microenvironment. The knowledge of how these lipids orchestrate the complex interactions between transformed epithelial cells and the surrounding stromal cells is crucial for understanding tumour evolution, progression and metastasis. Understanding the molecular mechanisms underlying the role of prostaglandins and other eicosanoids in cancer progression will help to develop more effective cancer chemopreventive and/or therapeutic agents.

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Year:  2010        PMID： 20168319      PMCID： PMC2898136          DOI： 10.1038/nrc2809

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  150 in total

1.  The pro-inflammatory mediator leukotriene D4 induces phosphatidylinositol 3-kinase and Rac-dependent migration of intestinal epithelial cells.

Authors:  Sailaja Paruchuri; Oliver Broom; Karim Dib; Anita Sjölander
Journal:  J Biol Chem       Date:  2005-01-18       Impact factor: 5.157

2.  The leukotriene B4 lipid chemoattractant receptor BLT1 defines antigen-primed T cells in humans.

Authors:  Sabina A Islam; Seddon Y Thomas; Christoph Hess; Benjamin D Medoff; Terry K Means; Christian Brander; Craig M Lilly; Andrew M Tager; Andrew D Luster
Journal:  Blood       Date:  2005-09-22       Impact factor: 22.113

3.  Prostaglandin E2 receptor subtype 2 (EP2) null mice are protected against murine lung tumorigenesis.

Authors:  Robert L Keith; Mark W Geraci; S Patrick Nana-Sinkam; Richard M Breyer; Tyler M Hudish; Amy M Meyer; Alvin M Malkinson; Lori D Dwyer-Nield
Journal:  Anticancer Res       Date:  2006 Jul-Aug       Impact factor: 2.480

4.  The inflammatory mediator leukotriene D4 induces beta-catenin signaling and its association with antiapoptotic Bcl-2 in intestinal epithelial cells.

Authors:  Maryna Mezhybovska; Katarina Wikström; John F Ohd; Anita Sjölander
Journal:  J Biol Chem       Date:  2006-01-05       Impact factor: 5.157

5.  Prostaglandin E2 regulates tumor angiogenesis in prostate cancer.

Authors:  Shalini Jain; Goutam Chakraborty; Remya Raja; Smita Kale; Gopal C Kundu
Journal:  Cancer Res       Date:  2008-10-01       Impact factor: 12.701

6.  Altered eicosanoid levels in human colon cancer.

Authors:  B Rigas; I S Goldman; L Levine
Journal:  J Lab Clin Med       Date:  1993-11

7.  The effect of cysteinyl leukotrienes on growth of eosinophil progenitors from peripheral blood and bone marrow of atopic subjects.

Authors:  Fausto Braccioni; Sandra C Dorman; Paul M O'byrne; Mark D Inman; Judah A Denburg; Krishnan Parameswaran; Adrian J Baatjes; Ronan Foley; Gail M Gauvreau
Journal:  J Allergy Clin Immunol       Date:  2002-07       Impact factor: 10.793

8.  Leukotrienes C4 and D4 promote angiogenesis via a receptor-mediated interaction.

Authors:  N E Tsopanoglou; E Pipili-Synetos; M E Maragoudakis
Journal:  Eur J Pharmacol       Date:  1994-06-02       Impact factor: 4.432

9.  Leukotriene D(4) activates MAPK through a Ras-independent but PKCepsilon-dependent pathway in intestinal epithelial cells.

Authors:  Sailaja Paruchuri; Bengt Hallberg; Maria Juhas; Christer Larsson; Anita Sjölander
Journal:  J Cell Sci       Date:  2002-05-01       Impact factor: 5.285

10.  Role of the parasite-derived prostaglandin D2 in the inhibition of epidermal Langerhans cell migration during schistosomiasis infection.

Authors:  V Angeli; C Faveeuw; O Roye; J Fontaine; E Teissier; A Capron; I Wolowczuk; M Capron; F Trottein
Journal:  J Exp Med       Date:  2001-05-21       Impact factor: 14.307
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  659 in total

1.  Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development.

Authors:  Ulrike Haas; Elisabeth Raschperger; Mats Hamberg; Bengt Samuelsson; Karl Tryggvason; Jesper Z Haeggström
Journal:  Proc Natl Acad Sci U S A       Date:  2011-12-05       Impact factor: 11.205

2.  ANGPTL4 induction by prostaglandin E2 under hypoxic conditions promotes colorectal cancer progression.

Authors:  Sun-Hee Kim; Yun-Yong Park; Sang-Wook Kim; Ju-Seog Lee; Dingzhi Wang; Raymond N DuBois
Journal:  Cancer Res       Date:  2011-09-21       Impact factor: 12.701

Review 3.  Basic aspects of tumor cell fatty acid-regulated signaling and transcription factors.

Authors:  Andrea Comba; Yi-Hui Lin; Aldo Renato Eynard; Mirta Ana Valentich; Martín Ernesto Fernandez-Zapico; Marìa Eugenia Pasqualini
Journal:  Cancer Metastasis Rev       Date:  2011-12       Impact factor: 9.264

4.  Associations between obesity and cancer: the role of fatty acid synthase.

Authors:  Dingzhi Wang; Raymond N Dubois
Journal:  J Natl Cancer Inst       Date:  2012-02-06       Impact factor: 13.506

5.  Noninvasive imaging identifies new roles for cyclooxygenase-2 in choline and lipid metabolism of human breast cancer cells.

Authors:  Tariq Shah; Ioannis Stasinopoulos; Flonne Wildes; Samata Kakkad; Dmitri Artemov; Zaver M Bhujwalla
Journal:  NMR Biomed       Date:  2011-09-22       Impact factor: 4.044

Review 6.  Lysophospholipid acyltransferases and leukotriene biosynthesis: intersection of the Lands cycle and the arachidonate PI cycle.

Authors:  Robert C Murphy; Giancarlo Folco
Journal:  J Lipid Res       Date:  2019-01-03       Impact factor: 5.922

7.  Celecoxib enhances the efficacy of 15-hydroxyprostaglandin dehydrogenase gene therapy in treating murine breast cancer.

Authors:  Binglan Zhang; Xuelei Ma; Zhimian Li; Xiang Gao; Fengtian Wang; Lei Liu; Guobo Shen; Yaxiong Sang; Minmin Li; Yuli Li; Jingyi Zhao; Yuquan Wei
Journal:  J Cancer Res Clin Oncol       Date:  2013-02-06       Impact factor: 4.553

8.  Arsenic promotes the COX2/PGE2-SOX2 axis to increase the malignant stemness properties of urothelial cells.

Authors:  Akira Ooki; Asma Begum; Luigi Marchionni; Christopher J VandenBussche; Shifeng Mao; Max Kates; Mohammad Obaidul Hoque
Journal:  Int J Cancer       Date:  2018-02-14       Impact factor: 7.396

Review 9.  Leukotriene receptors as potential therapeutic targets.

Authors:  Takehiko Yokomizo; Motonao Nakamura; Takao Shimizu
Journal:  J Clin Invest       Date:  2018-05-14       Impact factor: 14.808

10.  Systems-Level Lipid Analysis Methodologies for Qualitative and Quantitative Investigation of Lipid Signaling Events During Wound Healing.

Authors:  Dayanjan S Wijesinghe; Charles E Chalfant
Journal:  Adv Wound Care (New Rochelle)       Date:  2013-11       Impact factor: 4.730
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