Literature DB >> 26709069

Flattening filter free technique in breath-hold treatments of left-sided breast cancer: The effect on beam-on time and dose distributions.

Tuomas Koivumäki1, Janne Heikkilä2, Anssi Väänänen2, Kristiina Koskela2, Saara Sillanmäki3, Jan Seppälä2.   

Abstract

BACKGROUND AND
PURPOSE: The use of flattening filter free (FFF) beams has potential to speed up deep-inspiration breath-hold treatments. In this study, the beam-on time and dose characteristics of left-sided breast treatment plans with FFF and flattened beams were evaluated.
MATERIAL AND METHODS: Twelve plans were generated for 20 patients. The techniques utilized were volumetric modulated arc therapy with two limited tangential arcs (tVMAT) and tangential intensity modulated radiotherapy with dynamic (dIMRT) as well as step-and-shoot (FinF) dose delivery. Each technique was planned with FFF and flattened beams with 6 and 10MV photons. All plans were irradiated and the beam-on times were measured. Dose characteristics of planning target volume (PTV) and organs at risk (OAR) were evaluated.
RESULTS: The mean beam-on times were reduced by 18-39% using FFF. Mean PTV dose coverage was least reduced with tVMAT (0.6-0.8%) compared to dIMRT (4%) and FinF (5.6-9.1%), when FFF beams were used instead of flattened beams. Only small differences were observed in OAR doses between equivalent plans (FFF vs. flattened).
CONCLUSIONS: A significant reduction was observed in beam-on time when utilizing FFF beams with tVMAT, dIMRT and FinF. tVMAT was the only technique for which the use of FFF did not degrade the treatment plan dose distributions.
Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Breast cancer; Deep-inspiration breath-hold; Flattening filter free; Volumetric modulated arc therapy

Mesh:

Year:  2015        PMID: 26709069     DOI: 10.1016/j.radonc.2015.11.032

Source DB:  PubMed          Journal:  Radiother Oncol        ISSN: 0167-8140            Impact factor:   6.280


  6 in total

1.  Dosimetric Comparison of Sequential Versus Simultaneous-integrated Boost in Early-stage Breast Cancer Patients Treated With Breast-conserving Surgery.

Authors:  Cem Onal; Esma Efe; Ozan C Guler; Berna A Yildirim
Journal:  In Vivo       Date:  2019 Nov-Dec       Impact factor: 2.155

2.  Treatment Planning With Unflattened as Compared to Flattenedzzm321990Beams for Bilateral Carcinoma of the Breast

Authors:  Suresh Tamilarasu; Madeswaran Saminathan; S K Sharma; Anjali P; Abhinav Dewan
Journal:  Asian Pac J Cancer Prev       Date:  2017-05-01

3.  Prolonging deep inspiration breath-hold time to 3 min during radiotherapy, a simple solution.

Authors:  Vincent Vakaet; Hans Van Hulle; Max Schoepen; Els Van Caelenberg; Annick Van Greveling; Jeroen Holvoet; Chris Monten; Luc De Baerdemaeker; Wilfried De Neve; Marc Coppens; Liv Veldeman
Journal:  Clin Transl Radiat Oncol       Date:  2021-02-23

4.  Using flattening filter free beams in electronic tissue compensation whole breast irradiation with deep inspiration breath hold.

Authors:  Sarah B Wisnoskie; Xiaoying Liang; Andrew O Wahl; Nathan R Bennion; Andrew D Granatowicz; Sumin Zhou; Dandan Zheng
Journal:  J Appl Clin Med Phys       Date:  2020-12-03       Impact factor: 2.102

5.  Flattening Filter-Free Volumetric-Modulated Arc Radiotherapy for Left-Sided Whole-Breast, Partial-Breast, and Postmastectomy Irradiations.

Authors:  Rui Zhang; Yibo Xie; Chloe DiTusa; Raymond Ohler; David Heins; Daniel Bourgeois; Beibei Guo
Journal:  J Med Phys       Date:  2022-08-05

6.  Simultaneous integrated boost (SIB) radiation therapy of right sided breast cancer with and without flattening filter - A treatment planning study.

Authors:  Johannes Maier; Bernadette Knott; Manuel Maerz; Rainer Loeschel; Oliver Koelbl; Barbara Dobler
Journal:  Radiat Oncol       Date:  2016-08-31       Impact factor: 3.481

  6 in total

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