Literature DB >> 26708421

Diverse roles of the nucleic acid-binding protein KHSRP in cell differentiation and disease.

Paola Briata1, Domenico Bordo1, Margherita Puppo1, Franco Gorlero2,3, Martina Rossi1, Nora Perrone-Bizzozero4, Roberto Gherzi1.   

Abstract

The single-stranded nucleic acid-binding protein KHSRP (KH-type splicing regulatory protein) modulates RNA life and gene expression at various levels. KHSRP controls important cellular functions as different as proliferation, differentiation, metabolism, and response to infectious agents. We summarize and discuss experimental evidence providing a potential link between changes in KHSRP expression/function and human diseases including neuromuscular disorders, obesity, type II diabetes, and cancer.
© 2015 Wiley Periodicals, Inc.

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Year:  2015        PMID： 26708421      PMCID： PMC4770880          DOI： 10.1002/wrna.1327

Source DB:  PubMed          Journal:  Wiley Interdiscip Rev RNA        ISSN： 1757-7004            Impact factor:   9.957


  77 in total

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4.  Identification of precursor microRNAs within distal axons of sensory neuron.

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Journal:  Nucleic Acids Res       Date:  2014-10-29       Impact factor: 16.971

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Authors:  Franziska Bollmann; Julia Art; Jenny Henke; Katharina Schrick; Verena Besche; Matthias Bros; Huige Li; Daniel Siuda; Norbert Handler; Florian Bauer; Thomas Erker; Felix Behnke; Bettina Mönch; Lorena Härdle; Markus Hoffmann; Ching-Yi Chen; Ulrich Förstermann; Verena M Dirsch; Oliver Werz; Hartmut Kleinert; Andrea Pautz
Journal:  Nucleic Acids Res       Date:  2014-10-28       Impact factor: 16.971

9.  The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs.

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  23 in total

1.  KSRP modulates melanoma growth and efficacy of vemurafenib.

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Journal:  Mol Cancer Res       Date:  2020-06-19       Impact factor: 5.852

4.  KH-type splicing regulatory protein (KHSRP) contributes to tumorigenesis by promoting miR-26a maturation in small cell lung cancer.

Authors:  Lihua Tong; Yingshan Luo; Ting Wei; Linlang Guo; Haihong Wang; Weiliang Zhu; Jian Zhang
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5.  KH-Type Splicing Regulatory Protein Controls Colorectal Cancer Cell Growth and Modulates the Tumor Microenvironment.

Authors:  Francesco Caiazza; Katarzyna Oficjalska; Miriam Tosetto; James J Phelan; Sinéad Noonan; Petra Martin; Kate Killick; Laura Breen; Fiona O'Neill; Blathnaid Nolan; Simon Furney; Robert Power; David Fennelly; Charles S Craik; Jacintha O'Sullivan; Kieran Sheahan; Glen A Doherty; Elizabeth J Ryan
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Review 9.  The master regulator FUBP1: its emerging role in normal cell function and malignant development.

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10.  KH-type splicing regulatory protein is involved in esophageal squamous cell carcinoma progression.

Authors:  Yuji Fujita; Kiyoshi Masuda; Junichi Hamada; Katsutoshi Shoda; Takuya Naruto; Satoshi Hamada; Yuko Miyakami; Tomohiro Kohmoto; Miki Watanabe; Rizu Takahashi; Shoichiro Tange; Masako Saito; Yasusei Kudo; Hitoshi Fujiwara; Daisuke Ichikawa; Akira Tangoku; Eigo Otsuji; Issei Imoto
Journal:  Oncotarget       Date:  2017-09-15
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