Christof Högg1,2, Moritz Maier3,4, Katherina Dettinger-Maier3,4, Xiuli He3, Lena Rothmund3,4, Kai Kehe4,5, Reinhard Hickel3, Franz-Xaver Reichl3,4. 1. Department of Operative/Restorative Dentistry, Periodontology and Pedodontics, Ludwig-Maximilians-University of Munich, Goethestr 70, D-80336, Munich, Germany. christof.hoegg@lrz.uni-muenchen.de. 2. Walther-Straub-Institute of Pharmacology and Toxicology, Ludwig-Maximilians-University of Munich, Nussbaumstr 26, 80336, Munich, Germany. christof.hoegg@lrz.uni-muenchen.de. 3. Department of Operative/Restorative Dentistry, Periodontology and Pedodontics, Ludwig-Maximilians-University of Munich, Goethestr 70, D-80336, Munich, Germany. 4. Walther-Straub-Institute of Pharmacology and Toxicology, Ludwig-Maximilians-University of Munich, Nussbaumstr 26, 80336, Munich, Germany. 5. Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstr. 11, 80937, Munich, Germany.
Abstract
OBJECTIVES: Polymerization of resin-based composites (RBCs) is incomplete. The aim of the present study was to determine whether a longer curing time than recommended by the manufacturer influences the amount of released composite components of RBCs. MATERIALS AND METHODS: The composites Clearfil AP-X and els extra low shrinkage were polymerized for six different curing times: 4, 10, 20, 40, 100, and 200 s. Light curing time recommended by the manufacturer for both composites is 20 s. Subsequently, samples were eluted in methanol and water for 1, 3, and 7 days and analyzed by gas chromatography/mass spectrometry (GC/MS). RESULTS: For Clearfil AP-X ethylene glycol dimethacrylate (EGDMA), diethylene glycol dimethacrylate (DEGDMA), triethylene glycol dimethacrylate (TEGDMA), 2-hydroxy-4-methoxybenzophenone (HMBP), camphorquinone (CQ) and 2,6-di-tert-butyl-4-methylphenol (BHT) were detected in methanol. In the aqueous eluate, only TEGDMA was detected. In els extra low shrinkage, HMBP, BHT, and CQ were detected in methanol. CONCLUSION: Increasing the curing time compared to recommendation of the manufacturer reduces the release of most composite components. This could result in less exposure to human due to these substances. CLINICAL RELEVANCE: Methacrylates are classified as potential allergens. An increasing number of dentists and patients show allergic reaction to methacrylates. Therefore, a reduced elution of composite components is an advantage.
OBJECTIVES: Polymerization of resin-based composites (RBCs) is incomplete. The aim of the present study was to determine whether a longer curing time than recommended by the manufacturer influences the amount of released composite components of RBCs. MATERIALS AND METHODS: The composites Clearfil AP-X and els extra low shrinkage were polymerized for six different curing times: 4, 10, 20, 40, 100, and 200 s. Light curing time recommended by the manufacturer for both composites is 20 s. Subsequently, samples were eluted in methanol and water for 1, 3, and 7 days and analyzed by gas chromatography/mass spectrometry (GC/MS). RESULTS: For Clearfil AP-X ethylene glycol dimethacrylate (EGDMA), diethylene glycol dimethacrylate (DEGDMA), triethylene glycol dimethacrylate (TEGDMA), 2-hydroxy-4-methoxybenzophenone (HMBP), camphorquinone (CQ) and 2,6-di-tert-butyl-4-methylphenol (BHT) were detected in methanol. In the aqueous eluate, only TEGDMA was detected. In els extra low shrinkage, HMBP, BHT, and CQ were detected in methanol. CONCLUSION: Increasing the curing time compared to recommendation of the manufacturer reduces the release of most composite components. This could result in less exposure to human due to these substances. CLINICAL RELEVANCE: Methacrylates are classified as potential allergens. An increasing number of dentists and patients show allergic reaction to methacrylates. Therefore, a reduced elution of composite components is an advantage.
Authors: Angela Di Pietro; Giuseppa Visalli; Sebastiano La Maestra; Rosanna Micale; Barbara Baluce; Giovanni Matarese; Luciano Cingano; Maria Elena Scoglio Journal: Mutat Res Date: 2007-11-22 Impact factor: 2.433
Authors: Prashanthi Sampath Madhyastha; Dilip G Naik; Ravindra Kotian; Divya Padma; N Srikant; Kumar M R Bhat Journal: J Clin Diagn Res Date: 2015-01-01
Authors: Mario Seiss; Siegfried Nitz; Norbert Kleinsasser; Jeroen T M Buters; Heidrun Behrendt; Reinhard Hickel; Franz X Reichl Journal: Dent Mater Date: 2006-02-02 Impact factor: 5.304