OBJECTIVE: The introduction of an electronic brachytherapy delivery system into an existing general dermatology practice is described. Radiobiologic rational for the dose fractionation schedule is detailed. DESIGN: A miniaturized 50keV x-ray tube and delivery system are United States Food and Drug Administration cleared for nonmelanoma skin cancer. The device is introduced into an existing multi-physician dermatology practice in a standard unshielded treatment room. SETTING: A multi-site, multi-physician dermatology practice Results: Fifteen months following introduction of the system, a total of 524 nonmelanoma skin cancer patients have been treated. At 12.5 months follow-up, there have been four recurrences and cosmesis has been excellent. CONCLUSIONS: Advances in radiobiology and radiotechnology permit the treatment course to be given in eight fractions over four weeks. Radiation therapy for nonmelanoma skin cancer can now be given in an office setting as an alternative to Mohs surgery for appropriately selected patients. Results are comparable or better than those of surgery. Advances in radiobiology and radiotechnology permit the treatment course to be given in as few as eight fractions over four weeks. Patients are pleased with the convenience of the short course of therapy given in the office.
OBJECTIVE: The introduction of an electronic brachytherapy delivery system into an existing general dermatology practice is described. Radiobiologic rational for the dose fractionation schedule is detailed. DESIGN: A miniaturized 50keV x-ray tube and delivery system are United States Food and Drug Administration cleared for nonmelanoma skin cancer. The device is introduced into an existing multi-physician dermatology practice in a standard unshielded treatment room. SETTING: A multi-site, multi-physician dermatology practice Results: Fifteen months following introduction of the system, a total of 524 nonmelanoma skin cancerpatients have been treated. At 12.5 months follow-up, there have been four recurrences and cosmesis has been excellent. CONCLUSIONS: Advances in radiobiology and radiotechnology permit the treatment course to be given in eight fractions over four weeks. Radiation therapy for nonmelanoma skin cancer can now be given in an office setting as an alternative to Mohs surgery for appropriately selected patients. Results are comparable or better than those of surgery. Advances in radiobiology and radiotechnology permit the treatment course to be given in as few as eight fractions over four weeks. Patients are pleased with the convenience of the short course of therapy given in the office.
Authors: Rakesh R Patel; Peter D Beitsch; Timothy D Nichols; John D Lorenzetti; James C Wurzer; James C Tucker; George W Nunn; Susan J Laduzinsky; Morris A Kugler; Dwelvin L Simmons; Michael S Gilligan; Tapan Roy; Jonathon K Foley; John P Thropay; Mark William Odou; Bruce A Bornstein; Elizabeth P Tito; Manjeet Chadha; Susan K Boolbol; Steven C Lane; Julie G White Journal: Am J Clin Oncol Date: 2013-10 Impact factor: 2.339
Authors: Nicholas G Zaorsky; Charles T Lee; Eddie Zhang; Scott W Keith; Thomas J Galloway Journal: Radiother Oncol Date: 2017-08-23 Impact factor: 6.280
Authors: Anna O Likhacheva; Phillip M Devlin; Shervin M Shirvani; Christopher A Barker; Phillip Beron; Ajay Bhatnagar; Stephen W Doggett; Lawrence Hochman; Charles Hsu; Michael Kasper; Martin Keisch; Subhakar Mutyala; Bradley Prestidge; Silvia Rodriguez Villalba; Vershalee Shukla; Srinath Sundararaman; Mitchell Kamrava Journal: Brachytherapy Date: 2016-11-28 Impact factor: 2.362
Authors: Sofian Benkhaled; Dirk Van Gestel; Carolina Gomes da Silveira Cauduro; Samuel Palumbo; Veronique Del Marmol; Antoine Desmet Journal: Front Med (Lausanne) Date: 2022-06-27
Authors: Rosa Ballester-Sánchez; Olga Pons-Llanas; Cristian Candela-Juan; Blanca de Unamuno-Bustos; Francisco Javier Celada-Alvarez; Alejandro Tormo-Mico; Jose Perez-Calatayud; Rafael Botella-Estrada Journal: J Contemp Brachytherapy Date: 2017-06-05