| Literature DB >> 2669984 |
Abstract
Platelet-activating factor (PAF) exerts its actions through activation of specific membrane binding sites found in a variety of tissues, including hypothalamus and endometrium. PAF has been identified in several reproductive tissues (i.e. embryo, ovary, uterus, and spermatozoon). In the uterus, PAF levels are hormonally controlled, being elevated by progesterone and prostaglandin E2 (PGE2). Antagonists of PAF interfere with sperm function, ovulation, and implantation. The available evidence suggests that PAF may be an important physiological regulator in reproduction.Entities:
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Year: 1989 PMID: 2669984 DOI: 10.1095/biolreprod40.5.907
Source DB: PubMed Journal: Biol Reprod ISSN: 0006-3363 Impact factor: 4.285