Asja E Schollenberger1, Judith Karschin2, Tobias Meile3, Markus A Küper4, Alfred Königsrainer3, Stephan C Bischoff5. 1. Centre of Nutritional Medicine, University of Hohenheim and University Hospital of Tübingen, Tübingen, Germany. 2. Department of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany. 3. Department of General, Visceral and Transplant Surgery, University Hospital Tübingen, Tübingen, Germany. 4. Department of General and Visceral Surgery, Bundeswehrkrankenhaus, Berlin, Germany. 5. Department of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany. Electronic address: bischoff.stephan@uni-hohenheim.de.
Abstract
OBJECTIVES: Bariatric patients are at risk of protein deficiency. The aim of this study was to determine possible benefits of postoperative protein supplementation weight reduction, body composition, and protein status. METHODS:Twenty obese patients who underwent bariatric surgery were randomized either to the protein (PRO) group, which received a daily protein supplement over 6 months postoperatively, or to the control (CON) group, which received an isocaloric placebo in a double-blind fashion. Data on protein and energy intake, body weight, body composition, blood proteins, and grip force was collected preinterventionally and at 1, 3, and 6 months postoperatively. RESULTS: In both groups body weight was significantly reduced to a similar extent (after 6 months: PRO group 25.4 ± 7.2%, CON group 20.9 ± 3.9%; intergroup comparison P > 0.05). Protein intake was steadily increased in the PRO group, but not in the CON group, and reached maximum at month 6 (25.4 ± 3.7% of energy intake versus 15.8 ± 4.4%; P < 0.001). In the PRO group, body fat mass loss was higher than that in the CON group (79% of absolute weight loss versus 73%; P = 0.02) while lean body mass loss was less pronounced (21% versus 27%, P = 0.05). Blood proteins and grip force did not differ at any time point between the two groups. CONCLUSIONS: The present study suggests that protein supplementationafter bariatric surgery improves body composition by enhancing loss of body fat mass and reducing loss of lean body mass within the 6 months follow up.
RCT Entities:
OBJECTIVES: Bariatric patients are at risk of protein deficiency. The aim of this study was to determine possible benefits of postoperative protein supplementation weight reduction, body composition, and protein status. METHODS: Twenty obesepatients who underwent bariatric surgery were randomized either to the protein (PRO) group, which received a daily protein supplement over 6 months postoperatively, or to the control (CON) group, which received an isocaloric placebo in a double-blind fashion. Data on protein and energy intake, body weight, body composition, blood proteins, and grip force was collected preinterventionally and at 1, 3, and 6 months postoperatively. RESULTS: In both groups body weight was significantly reduced to a similar extent (after 6 months: PRO group 25.4 ± 7.2%, CON group 20.9 ± 3.9%; intergroup comparison P > 0.05). Protein intake was steadily increased in the PRO group, but not in the CON group, and reached maximum at month 6 (25.4 ± 3.7% of energy intake versus 15.8 ± 4.4%; P < 0.001). In the PRO group, body fat mass loss was higher than that in the CON group (79% of absolute weight loss versus 73%; P = 0.02) while lean body mass loss was less pronounced (21% versus 27%, P = 0.05). Blood proteins and grip force did not differ at any time point between the two groups. CONCLUSIONS: The present study suggests that protein supplementation after bariatric surgery improves body composition by enhancing loss of body fat mass and reducing loss of lean body mass within the 6 months follow up.
Authors: Luigi Schiavo; Giuseppe Scalera; Vincenzo Pilone; Gabriele De Sena; Vincenzo Quagliariello; Antonio Iannelli; Alfonso Barbarisi Journal: Obes Surg Date: 2017-04 Impact factor: 4.129