| Literature DB >> 26682499 |
Todd M Greco1, Ileana M Cristea2.
Abstract
Over the past decade, it became evident that proteins perform critical functions as components of specialized macromolecular complexes. Here, we discuss a recent study by Wan and colleagues, which highlights the significance of protein complexes by studying their conservation in organisms separated by up to a billion years of evolution.Entities:
Keywords: Protein interactions; evolution; interactome; macromolecular complex; mass spectrometry; protein-protein interaction
Mesh:
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Year: 2015 PMID: 26682499 PMCID: PMC4706493 DOI: 10.1016/j.tibs.2015.11.007
Source DB: PubMed Journal: Trends Biochem Sci ISSN: 0968-0004 Impact factor: 13.807