Literature DB >> 2668067

Enhancement of proteinase-mediated degradation of proteins modified by chlorination.

E Olszowska1, S Olszowski, J M Zgliczyński, T Stelmaszyńska.   

Abstract

1. Pretreatment of some proteins (albumin, immunoglobulin G, elastin and fibrinogen) with hypochlorite or with the MPO-H2O2-Cl- system increased their susceptibility to proteolysis by trypsin, chymotrypsin or elastase. 2. The optimal activities of these three proteinases were attained at a different extent of albumin chlorination. 3. Elastase was found to develop a specially efficient activity towards chlorinated albumin or chlorinated elastin being by itself resistant to chlorinating species.

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Year:  1989        PMID: 2668067     DOI: 10.1016/0020-711x(89)90213-9

Source DB:  PubMed          Journal:  Int J Biochem        ISSN: 0020-711X


  4 in total

1.  Enhancement of trinitrophenyl-specific humoral response to TNP proteins as the result of carrier chlorination.

Authors:  J Marcinkiewicz; E Olszowska; S Olszowski; J M Zgliczynski
Journal:  Immunology       Date:  1992-07       Impact factor: 7.397

2.  Differential effects of chlorination of bacteria on their capacity to generate NO, TNF-alpha and IL-6 in macrophages.

Authors:  J Marcinkiewicz; B Czajkowska; A Grabowska; A Kasprowicz; B Kociszewska
Journal:  Immunology       Date:  1994-12       Impact factor: 7.397

3.  Oxidation of defined antigens allows protein unfolding and increases both proteolytic processing and exposes peptide epitopes which are recognized by specific T cells.

Authors:  E Carrasco-Marín; J E Paz-Miguel; P López-Mato; C Alvarez-Domínguez; F Leyva-Cobián
Journal:  Immunology       Date:  1998-11       Impact factor: 7.397

4.  Modulation of antigen-specific T-cell activation in vitro by taurine chloramine.

Authors:  J Marcinkiewicz; A Grabowska; B M Chain
Journal:  Immunology       Date:  1998-07       Impact factor: 7.397

  4 in total

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