Young-Kyun Kim1, Jong-Ho Lee2, In-Woong Um3, Woo-Jin Cho4. 1. Professor, Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam; Professor, Department of Dentistry and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea. 2. Professor, Department of Dentistry and Dental Research Institute, School of Dentistry, Seoul National University; and Professor, Department of Oral and Maxillofacial Surgery, Seoul National University Dental Hospital, Seoul, Korea. 3. Director, R&D Institute, Korea Tooth Bank, Seoul, Korea. Electronic address: h-bmp@hanmail.net. 4. Researcher, R&D Institute, Korea Tooth Bank, Seoul, Korea.
Abstract
PURPOSE: This case report reviews the long-term clinical outcomes of using demineralized dentin matrix (autogenous tooth bone graft material [AutoBT]) in 5 cases that were first reported in 2010. MATERIALS AND METHODS: Cone-beam computerized tomography was used to measure the height and width of the graft to determine the change in bone area from immediately after surgery to final follow-up (average, 5 yr 5.8 months). Corticocancellous bone formation and marginal bone resorption also were evaluated histologically 3 to 6 months after grafting, which focused mainly on remodeling capacities. RESULTS: Decreases in buccal height and alveolar ridge width ranged from -0.4 to -3.3 mm and from -0.4 to -4.2 mm, respectively. The change in bone area ranged from -8.1 to -36.2%. Corticocancellous bone had formed and was maintained successfully except for 1 mm of buccal marginal bone resorption in 1 case followed for 6 years 7 months. CONCLUSION: AutoBT, which was first reported for guided bone regeneration, showed that the corticocancellous bone that had formed had been maintained successfully with an implant after an average follow-up of 5 years. Although the number of samples was small, the results were consistent with those of other short-term follow-up studies on AutoBT.
PURPOSE: This case report reviews the long-term clinical outcomes of using demineralized dentin matrix (autogenous tooth bone graft material [AutoBT]) in 5 cases that were first reported in 2010. MATERIALS AND METHODS: Cone-beam computerized tomography was used to measure the height and width of the graft to determine the change in bone area from immediately after surgery to final follow-up (average, 5 yr 5.8 months). Corticocancellous bone formation and marginal bone resorption also were evaluated histologically 3 to 6 months after grafting, which focused mainly on remodeling capacities. RESULTS: Decreases in buccal height and alveolar ridge width ranged from -0.4 to -3.3 mm and from -0.4 to -4.2 mm, respectively. The change in bone area ranged from -8.1 to -36.2%. Corticocancellous bone had formed and was maintained successfully except for 1 mm of buccal marginal bone resorption in 1 case followed for 6 years 7 months. CONCLUSION: AutoBT, which was first reported for guided bone regeneration, showed that the corticocancellous bone that had formed had been maintained successfully with an implant after an average follow-up of 5 years. Although the number of samples was small, the results were consistent with those of other short-term follow-up studies on AutoBT.
Authors: Mohammed E Grawish; Lamyaa M Grawish; Hala M Grawish; Mahmoud M Grawish; Ahmed A Holiel; Nessma Sultan; Salwa A El-Negoly Journal: Tissue Eng Regen Med Date: 2022-04-16 Impact factor: 4.451
Authors: P Gual-Vaqués; C Polis-Yanes; A Estrugo-Devesa; R Ayuso-Montero; A Mari-Roig; J López-López Journal: Med Oral Patol Oral Cir Bucal Date: 2018-01-01