Johannes P Koren1, Johannes Herta2, Susanne Pirker1, Franz Fürbass3, Manfred Hartmann3, Tilmann Kluge3, Christoph Baumgartner4. 1. Karl Landsteiner Institute for Clinical Epilepsy Research and Cognitive Neurology, 2nd Neurological Department, General Hospital Hietzing with Neurological Center Rosenhügel, Vienna, Austria. 2. Department of Neurosurgery, Medical University of Vienna, Vienna, Austria. 3. Austrian Institute of Technology GmbH (AIT), Safety & Security Department, Vienna, Austria. 4. Karl Landsteiner Institute for Clinical Epilepsy Research and Cognitive Neurology, 2nd Neurological Department, General Hospital Hietzing with Neurological Center Rosenhügel, Vienna, Austria. Electronic address: christoph.baumgartner@wienkav.at.
Abstract
OBJECTIVES: To study periodic and rhythmic EEG patterns classified according to Standardized Critical Care EEG Terminology (SCCET) of the American Clinical Neurophysiology Society and their relationship to electrographic seizures. METHODS: We classified 655 routine EEGs in 371 consecutive critically ill neurological patients into (1) normal EEGs or EEGs with non-specific abnormalities or interictal epileptiform discharges, (2) EEGs containing unequivocal ictal EEG patterns, and (3) EEGs showing rhythmic and periodic EEG patterns of 'ictal-interictal uncertainty' (RPPIIIU) according to SCCET. RESULTS: 313 patients (84.4%) showed normal EEGs, non-specific or interictal abnormalities, 14 patients (3.8%) had EEGs with at least one electrographic seizure, and 44 patients (11.8%) at least one EEG containing RPPIIIU, but no EEG with electrographic seizures. Electrographic seizures occurred in 11 of 55 patients (20%) with RPPIIIU, but only in 3 of 316 patients (0.9%) without RPPIIIU (p⩽0.001). Conversely, we observed RPPIIIU in 11 of 14 patients (78.6%) with electrographic seizures, but only in 44 of 357 patients (12.3%) without electrographic seizures (p⩽0.001). CONCLUSIONS: On routine-EEG in critically ill neurological patients RPPIIIU occur 3 times more frequently than electrographic seizures and are highly predictive for electrographic seizures. SIGNIFICANCE: RPPIIIU can serve as an indication for continuous EEG recordings.
OBJECTIVES: To study periodic and rhythmic EEG patterns classified according to Standardized Critical Care EEG Terminology (SCCET) of the American Clinical Neurophysiology Society and their relationship to electrographic seizures. METHODS: We classified 655 routine EEGs in 371 consecutive critically ill neurologicalpatients into (1) normal EEGs or EEGs with non-specific abnormalities or interictal epileptiform discharges, (2) EEGs containing unequivocal ictal EEG patterns, and (3) EEGs showing rhythmic and periodic EEG patterns of 'ictal-interictal uncertainty' (RPPIIIU) according to SCCET. RESULTS: 313 patients (84.4%) showed normal EEGs, non-specific or interictal abnormalities, 14 patients (3.8%) had EEGs with at least one electrographic seizure, and 44 patients (11.8%) at least one EEG containing RPPIIIU, but no EEG with electrographic seizures. Electrographic seizures occurred in 11 of 55 patients (20%) with RPPIIIU, but only in 3 of 316 patients (0.9%) without RPPIIIU (p⩽0.001). Conversely, we observed RPPIIIU in 11 of 14 patients (78.6%) with electrographic seizures, but only in 44 of 357 patients (12.3%) without electrographic seizures (p⩽0.001). CONCLUSIONS: On routine-EEG in critically ill neurologicalpatients RPPIIIU occur 3 times more frequently than electrographic seizures and are highly predictive for electrographic seizures. SIGNIFICANCE: RPPIIIU can serve as an indication for continuous EEG recordings.
Authors: Johannes Koren; Johannes Herta; Simone Draschtak; Georg Pötzl; Franz Fürbass; Manfred Hartmann; Tilmann Kluge; Andreas Gruber; Christoph Baumgartner Journal: Neurocrit Care Date: 2018-12 Impact factor: 3.210
Authors: Wendong Ge; Jin Jing; Sungtae An; Aline Herlopian; Marcus Ng; Aaron F Struck; Brian Appavu; Emily L Johnson; Gamaleldin Osman; Hiba A Haider; Ioannis Karakis; Jennifer A Kim; Jonathan J Halford; Monica B Dhakar; Rani A Sarkis; Christa B Swisher; Sarah Schmitt; Jong Woo Lee; Mohammad Tabaeizadeh; Andres Rodriguez; Nicolas Gaspard; Emily Gilmore; Susan T Herman; Peter W Kaplan; Jay Pathmanathan; Shenda Hong; Eric S Rosenthal; Sahar Zafar; Jimeng Sun; M Brandon Westover Journal: J Neurosci Methods Date: 2020-10-22 Impact factor: 2.390
Authors: Johannes P Koren; Johannes Herta; Franz Fürbass; Susanne Pirker; Veronika Reiner-Deitemyer; Franz Riederer; Julia Flechsenhar; Manfred Hartmann; Tilmann Kluge; Christoph Baumgartner Journal: Front Neurol Date: 2018-06-19 Impact factor: 4.003
Authors: Katharina M Busl; Lawrence J Hirsch; Carolina B Maciel; Fernanda J P Teixeira; Katie J Dickinson; Jessica C Spana; Lisa H Merck; Alejandro A Rabinstein; Robert Sergott; Guogen Shan; Guanhong Miao; Charles A Peloquin Journal: Neurol Res Pract Date: 2022-01-24