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Literature DB >> 26678610

Transcriptional kinases: Less is more (or less).

Thomas G Boyer¹.

Abstract

Mesh：

Substances：

Year: 2016 PMID： 26678610 DOI： 10.1038/nchembio.1985

Source DB: PubMed Journal: Nat Chem Biol ISSN： 1552-4450 Impact factor: 15.040

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8 in total

1. Cortistatin A is a high-affinity ligand of protein kinases ROCK, CDK8, and CDK11.

Authors: Victor J Cee; David Y-K Chen; Matthew R Lee; K C Nicolaou
Journal: Angew Chem Int Ed Engl Date: 2009 Impact factor: 15.336

2. Super-enhancers in the control of cell identity and disease.

Authors: Denes Hnisz; Brian J Abraham; Tong Ihn Lee; Ashley Lau; Violaine Saint-André; Alla A Sigova; Heather A Hoke; Richard A Young
Journal: Cell Date: 2013-10-10 Impact factor: 41.582

Review 3. Mediator kinase module and human tumorigenesis.

Authors: Alison D Clark; Marieke Oldenbroek; Thomas G Boyer
Journal: Crit Rev Biochem Mol Biol Date: 2015-07-16 Impact factor: 8.250

4. CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity.

Authors: Ron Firestein; Adam J Bass; So Young Kim; Ian F Dunn; Serena J Silver; Isil Guney; Ellen Freed; Azra H Ligon; Natalie Vena; Shuji Ogino; Milan G Chheda; Pablo Tamayo; Stephen Finn; Yashaswi Shrestha; Jesse S Boehm; Supriya Jain; Emeric Bojarski; Craig Mermel; Jordi Barretina; Jennifer A Chan; Jose Baselga; Josep Tabernero; David E Root; Charles S Fuchs; Massimo Loda; Ramesh A Shivdasani; Matthew Meyerson; William C Hahn
Journal: Nature Date: 2008-09-14 Impact factor: 49.962

5. Cdk8 deletion in the Apc(Min) murine tumour model represses EZH2 activity and accelerates tumourigenesis.

Authors: Mark L McCleland; Tim M Soukup; Scot D Liu; Jonathan H Esensten; Felipe de Sousa e Melo; Murat Yaylaoglu; Soren Warming; Merone Roose-Girma; Ron Firestein
Journal: J Pathol Date: 2015-09-24 Impact factor: 7.996

6. Mediator kinase inhibition further activates super-enhancer-associated genes in AML.

Authors: Henry E Pelish; Brian B Liau; Ioana I Nitulescu; Anupong Tangpeerachaikul; Zachary C Poss; Diogo H Da Silva; Brittany T Caruso; Alexander Arefolov; Olugbeminiyi Fadeyi; Amanda L Christie; Karrie Du; Deepti Banka; Elisabeth V Schneider; Anja Jestel; Ge Zou; Chong Si; Christopher C Ebmeier; Roderick T Bronson; Andrei V Krivtsov; Andrew G Myers; Nancy E Kohl; Andrew L Kung; Scott A Armstrong; Madeleine E Lemieux; Dylan J Taatjes; Matthew D Shair
Journal: Nature Date: 2015-09-28 Impact factor: 49.962

7. Discovery of potent, orally bioavailable, small-molecule inhibitors of WNT signaling from a cell-based pathway screen.

Authors: Aurélie Mallinger; Simon Crumpler; Mark Pichowicz; Dennis Waalboer; Mark Stubbs; Olajumoke Adeniji-Popoola; Bozena Wood; Elizabeth Smith; Ching Thai; Alan T Henley; Katrin Georgi; William Court; Steve Hobbs; Gary Box; Maria-Jesus Ortiz-Ruiz; Melanie Valenti; Alexis De Haven Brandon; Robert TePoele; Birgitta Leuthner; Paul Workman; Wynne Aherne; Oliver Poeschke; Trevor Dale; Dirk Wienke; Christina Esdar; Felix Rohdich; Florence Raynaud; Paul A Clarke; Suzanne A Eccles; Frank Stieber; Kai Schiemann; Julian Blagg
Journal: J Med Chem Date: 2015-02-13 Impact factor: 7.446

8. A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease.

Authors: Trevor Dale; Paul A Clarke; Christina Esdar; Dennis Waalboer; Olajumoke Adeniji-Popoola; Maria-Jesus Ortiz-Ruiz; Aurélie Mallinger; Rahul S Samant; Paul Czodrowski; Djordje Musil; Daniel Schwarz; Klaus Schneider; Mark Stubbs; Ken Ewan; Elizabeth Fraser; Robert TePoele; Will Court; Gary Box; Melanie Valenti; Alexis de Haven Brandon; Sharon Gowan; Felix Rohdich; Florence Raynaud; Richard Schneider; Oliver Poeschke; Andree Blaukat; Paul Workman; Kai Schiemann; Suzanne A Eccles; Dirk Wienke; Julian Blagg
Journal: Nat Chem Biol Date: 2015-10-26 Impact factor: 15.040

8 in total

1 in total

1. Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases.

Authors: Paul A Clarke; Maria-Jesus Ortiz-Ruiz; Robert TePoele; Olajumoke Adeniji-Popoola; Gary Box; Will Court; Stephanie Czasch; Samer El Bawab; Christina Esdar; Ken Ewan; Sharon Gowan; Alexis De Haven Brandon; Phillip Hewitt; Stephen M Hobbs; Wolfgang Kaufmann; Aurélie Mallinger; Florence Raynaud; Toby Roe; Felix Rohdich; Kai Schiemann; Stephanie Simon; Richard Schneider; Melanie Valenti; Stefan Weigt; Julian Blagg; Andree Blaukat; Trevor C Dale; Suzanne A Eccles; Stefan Hecht; Klaus Urbahns; Paul Workman; Dirk Wienke
Journal: Elife Date: 2016-12-09 Impact factor: 8.140

1 in total