| Literature DB >> 2667794 |
L M Shaw1.
Abstract
This review will focus on our current state of understanding of the cellular and molecular mechanisms by which CsA exerts immunosuppression and will present new information on: pharmacokinetic variability of CsA, selection of specimen and method for measuring CsA concentration, identity of CsA metabolites and their immunosuppressive and toxic activity, and the relationship between steady-state pre-dose concentrations of CsA in blood and response to treatment in transplant patients.Entities:
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Year: 1989 PMID: 2667794
Source DB: PubMed Journal: Clin Chem ISSN: 0009-9147 Impact factor: 8.327