Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The cyclosporins.

Literature DB >> 8851466

The cyclosporins.

Abstract

This review presents the progress and some aspects achieved during recent years with cyclosporin sources, chemistry, biological activities, side effects, biosynthesis and metabolism. Although incomplete the results indicate future research trends and some white spots to be studied in the near future to afford unique insights into cell biology and to improve the search for similar and even more specific agents based on rational drug design.

Entities: Chemical

Mesh：

Substances：

Year: 1995 PMID： 8851466 DOI： 10.1007/bf02816529

Source DB: PubMed Journal: Folia Microbiol (Praha) ISSN： 0015-5632 Impact factor: 2.099

154 in total

1. Biological effects of cyclosporin A: a new antilymphocytic agent.

Authors: J F Borel; C Feurer; H U Gubler; H Stähelin
Journal: Agents Actions Date: 1976-07

2. The effect of cyclosporine A on infection of susceptible cells by human immunodeficiency virus type 1.

Authors: M A Wainberg; A Dascal; N Blain; L Fitz-Gibbon; F Boulerice; K Numazaki; M Tremblay
Journal: Blood Date: 1988-12 Impact factor: 22.113

3. [Cyclosporin A, a Peptide Metabolite from Trichoderma polysporum (Link ex Pers.) Rifai, with a remarkable immunosuppressive activity].

Authors: A Rüegger; M Kuhn; H Lichti; H R Loosli; R Huguenin; C Quiquerez; A von Wartburg
Journal: Helv Chim Acta Date: 1976 Impact factor: 2.164

10. Intravenous glucose tolerance and pancreatic islet beta-cell function in patients with multiple sclerosis during 2-yr treatment with cyclosporin.

Authors: R P Robertson; G Franklin; L Nelson
Journal: Diabetes Date: 1989-01 Impact factor: 9.461

1 in total

1. Mitochondrial permeability transition during hypothermic to normothermic reperfusion in rat liver demonstrated by the protective effect of cyclosporin A.

Authors: N Leducq; M C Delmas-Beauvieux; I Bourdel-Marchasson; S Dufour; J L Gallis; P Canioni; P Diolez
Journal: Biochem J Date: 1998-12-01 Impact factor: 3.857

1 in total

The cyclosporins.

1. Biological effects of cyclosporin A: a new antilymphocytic agent.

2. The effect of cyclosporine A on infection of susceptible cells by human immunodeficiency virus type 1.

3. [Cyclosporin A, a Peptide Metabolite from Trichoderma polysporum (Link ex Pers.) Rifai, with a remarkable immunosuppressive activity].

Review 4. Cancer is a complication of severe immunosuppression.

Review 5. Cyclosporine drug interactions: a review.

6. Effects of the new anti-lymphocytic peptide cyclosporin A in animals.

7. Cyclosporin synthetase. The most complex peptide synthesizing multienzyme polypeptide so far described.

8. The interaction of cyclosporin and calmodulin.

9. Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man.

10. Intravenous glucose tolerance and pancreatic islet beta-cell function in patients with multiple sclerosis during 2-yr treatment with cyclosporin.

1. Mitochondrial permeability transition during hypothermic to normothermic reperfusion in rat liver demonstrated by the protective effect of cyclosporin A.