Literature DB >> 2667137

The location of DNA in RecA-DNA helical filaments.

E H Egelman1, X Yu.   

Abstract

The helical filament that the RecA protein of Escherichia coli forms around DNA is the active apparatus in protein-catalyzed homologous genetic recombination. The actual position of DNA within this complex has been unknown. Image analysis has been performed on electron micrographs of filaments of RecA on double-stranded DNA and on single-stranded DNA to visualize a difference that is consistent with one strand of the double-stranded DNA. This localization of the DNA gives additional information about the unusual structure of DNA in the complex with RecA protein.

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Year:  1989        PMID： 2667137     DOI： 10.1126/science.2667137

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  17 in total

1.  Polymerization and mechanical properties of single RecA-DNA filaments.

Authors:  M Hegner; S B Smith; C Bustamante
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-31       Impact factor: 11.205

2.  Fueling protein DNA interactions inside porous nanocontainers.

Authors:  Ibrahim Cisse; Burak Okumus; Chirlmin Joo; Taekjip Ha
Journal:  Proc Natl Acad Sci U S A       Date:  2007-06-11       Impact factor: 11.205

3.  Intercalators promote the binding of RecA protein to double-stranded DNA.

Authors:  R J Thresher; J D Griffith
Journal:  Proc Natl Acad Sci U S A       Date:  1990-07       Impact factor: 11.205

Review 4.  RecA: Regulation and Mechanism of a Molecular Search Engine.

Authors:  Jason C Bell; Stephen C Kowalczykowski
Journal:  Trends Biochem Sci       Date:  2016-05-04       Impact factor: 13.807

5.  RecA.oligonucleotide filaments bind in the minor groove of double-stranded DNA.

Authors:  R Baliga; J W Singleton; P B Dervan
Journal:  Proc Natl Acad Sci U S A       Date:  1995-10-24       Impact factor: 11.205

6.  Three-dimensional reconstruction of a co-complex of F-actin with antibody Fab fragments to actin's NH2 terminus.

Authors:  A Orlova; X Yu; E H Egelman
Journal:  Biophys J       Date:  1994-02       Impact factor: 4.033

Review 7.  Biochemistry of homologous recombination in Escherichia coli.

Authors:  S C Kowalczykowski; D A Dixon; A K Eggleston; S D Lauder; W M Rehrauer
Journal:  Microbiol Rev       Date:  1994-09

8.  Image analysis reveals that Escherichia coli RecA protein consists of two domains.

Authors:  X Yu; E H Egelman
Journal:  Biophys J       Date:  1990-03       Impact factor: 4.033

9.  A change in actin conformation associated with filament instability after Pi release.

Authors:  L D Belmont; A Orlova; D G Drubin; E H Egelman
Journal:  Proc Natl Acad Sci U S A       Date:  1999-01-05       Impact factor: 11.205

10.  Spiroplasma citri virus SpV1-derived cloning vector: deletion formation by illegitimate and homologous recombination in a spiroplasmal host strain which probably lacks a functional recA gene.

Authors:  A Marais; J M Bové; J Renaudin
Journal:  J Bacteriol       Date:  1996-02       Impact factor: 3.490
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