Literature DB >> 7479791

RecA.oligonucleotide filaments bind in the minor groove of double-stranded DNA.

R Baliga1, J W Singleton, P B Dervan.   

Abstract

Escherichia coli RecA protein, in the presence of ATP or its analog adenosine 5'-[gamma-thio]triphosphate, polymerizes on single-stranded DNA to form nucleoprotein filaments that can then bind to homologous sequences on duplex DNA. The three-stranded joint molecule formed as a result of this binding event is a key intermediate in general recombination. We have used affinity cleavage to examine this three-stranded joint by incorporating a single thymidine-EDTA.Fe (T*) into the oligonucleotide part of the filament. Our analysis of the cleavage patterns from the joint molecule reveals that the nucleoprotein filament binds in the minor groove of an extended Watson-Crick duplex.

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Year:  1995        PMID： 7479791      PMCID： PMC40803          DOI： 10.1073/pnas.92.22.10393

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  41 in total

1.  Probing the structure of a putative intermediate in homologous recombination: the third strand in the parallel DNA triplex is in contact with the major groove of the duplex.

Authors:  M G Kim; V B Zhurkin; R L Jernigan; R D Camerini-Otero
Journal:  J Mol Biol       Date:  1995-04-14       Impact factor: 5.469

2.  High-resolution structure of a DNA helix forming (C.G)*G base triplets.

Authors:  L Van Meervelt; D Vlieghe; A Dautant; B Gallois; G Précigoux; O Kennard
Journal:  Nature       Date:  1995-04-20       Impact factor: 49.962

3.  A parallel DNA triplex as a model for the intermediate in homologous recombination.

Authors:  V B Zhurkin; G Raghunathan; N B Ulyanov; R D Camerini-Otero; R L Jernigan
Journal:  J Mol Biol       Date:  1994-06-03       Impact factor: 5.469

4.  Occurrence of three-stranded DNA within a RecA protein filament.

Authors:  S K Jain; M M Cox; R B Inman
Journal:  J Biol Chem       Date:  1995-03-03       Impact factor: 5.157

5.  By searching processively RecA protein pairs DNA molecules that share a limited stretch of homology.

Authors:  D K Gonda; C M Radding
Journal:  Cell       Date:  1983-09       Impact factor: 41.582

Review 6.  Structure and function of RecA-DNA complexes.

Authors:  A Stasiak; E H Egelman
Journal:  Experientia       Date:  1994-03-15

7.  Homologous pairing and DNA strand-exchange proteins.

Authors:  S C Kowalczykowski; A K Eggleston
Journal:  Annu Rev Biochem       Date:  1994       Impact factor: 23.643

8.  Role of RecA protein spiral filaments in genetic recombination.

Authors:  P Howard-Flanders; S C West; A Stasiak
Journal:  Nature       Date:  1984 May 17-23       Impact factor: 49.962

9.  Electron microscopic visualization of recA-DNA filaments: evidence for a cyclic extension of duplex DNA.

Authors:  K Dunn; S Chrysogelos; J Griffith
Journal:  Cell       Date:  1982-04       Impact factor: 41.582

10.  Visualization of recA protein and its association with DNA: a priming effect of single-strand-binding protein.

Authors:  J Flory; C M Radding
Journal:  Cell       Date:  1982-04       Impact factor: 41.582
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  9 in total

1.  A molecular model for RecA-promoted strand exchange via parallel triple-stranded helices.

Authors:  G Bertucat; R Lavery; C Prévost
Journal:  Biophys J       Date:  1999-09       Impact factor: 4.033

2.  Topological testing of the mechanism of homology search promoted by RecA protein.

Authors:  L Cai; U Marquardt; Z Zhang; M J Taisey; J Chen
Journal:  Nucleic Acids Res       Date:  2001-03-15       Impact factor: 16.971

Review 3.  Homologous genetic recombination as an intrinsic dynamic property of a DNA structure induced by RecA/Rad51-family proteins: a possible advantage of DNA over RNA as genomic material.

Authors:  T Shibata; T Nishinaka; T Mikawa; H Aihara; H Kurumizaka; S Yokoyama; Y Ito
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-17       Impact factor: 11.205

4.  Base pair switching by interconversion of sugar puckers in DNA extended by proteins of RecA-family: a model for homology search in homologous genetic recombination.

Authors:  T Nishinaka; A Shinohara; Y Ito; S Yokoyama; T Shibata
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-15       Impact factor: 11.205

Review 5.  Recombinational repair of DNA damage in Escherichia coli and bacteriophage lambda.

Authors:  A Kuzminov
Journal:  Microbiol Mol Biol Rev       Date:  1999-12       Impact factor: 11.056

6.  Parallel and antiparallel A*A-T intramolecular triple helices.

Authors:  C Dagneaux; H Gousset; A K Shchyolkina; M Ouali; R Letellier; J Liquier; V L Florentiev; E Taillandier
Journal:  Nucleic Acids Res       Date:  1996-11-15       Impact factor: 16.971

7.  Modeling the early stage of DNA sequence recognition within RecA nucleoprotein filaments.

Authors:  Adrien Saladin; Christopher Amourda; Pierre Poulain; Nicolas Férey; Marc Baaden; Martin Zacharias; Olivier Delalande; Chantal Prévost
Journal:  Nucleic Acids Res       Date:  2010-05-27       Impact factor: 16.971

Review 8.  The democratization of gene editing: Insights from site-specific cleavage and double-strand break repair.

Authors:  Maria Jasin; James E Haber
Journal:  DNA Repair (Amst)       Date:  2016-05-12

9.  The ATPase activity of E. coli RecA prevents accumulation of toxic complexes formed by erroneous binding to undamaged double stranded DNA.

Authors:  Daniil V Gataulin; Jeffrey N Carey; Junya Li; Parisha Shah; Jennifer T Grubb; Douglas K Bishop
Journal:  Nucleic Acids Res       Date:  2018-10-12       Impact factor: 16.971
  9 in total

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