| Literature DB >> 26666924 |
Ibai Los-Arcos1, Carles Pigrau2, Dolors Rodríguez-Pardo2, Nuria Fernández-Hidalgo2, Antonia Andreu3, Nieves Larrosa3, Benito Almirante2.
Abstract
This is a retrospective study of 15 difficult-to-treat (i.e., exhibiting previous failure, patient side effects, or resistance to ciprofloxacin and co-trimoxazole) chronic bacterial prostatitis infections (5 patients with multidrug-resistant Enterobacteriaceae [MDRE]) receiving fosfomycin-tromethamine at a dose of 3 g per 48 to 72 h for 6 weeks. After a median follow-up of 20 months, 7 patients (47%) had a clinical response, and 8 patients (53%) had persistent microbiological eradication; 4/5 patients with MDRE isolates achieved eradication. There were no side effects. Fosfomycin-tromethamine is a possible alternative therapy for chronic bacterial prostatitis.Entities:
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Year: 2015 PMID: 26666924 PMCID: PMC4776017 DOI: 10.1128/AAC.02611-15
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191