Arpit Doshi1, D M Tripathi2. 1. Department of Pediatrics, H. Bhagwati Municipal Hospital, Borivali West, Mumbai, Maharashtra, 400092, India. docarpit@yahoo.com. 2. Department of Allergy, Bombay Hospital, Institute of Postgraduate Medical Sciences, Mumbai, India.
Abstract
OBJECTIVE: To identify house dust mite (HDM) sensitivity by skin prick test in children with allergic rhinitis, allergic wheezing and eczema. METHODS: In this prospective study, children with persistent or recurrent allergic symptoms of rhinitis, wheezing and eczema were enrolled to undergo skin prick testing. Sensitivity was checked for three mites: Dermatophagoide farinae, Dermatophagoide pteronyssinus, and Blomia tropicalis. RESULTS: Total 92 children underwent skin prick test; 49 (53.2 %) showed significant positivity to one or more dust mite. In the HDM sensitized group, a positive family history of allergic disorders was present in 32 children (65.3 %). In the HDM sensitized group, 18 (36.7 %) children had allergic rhinitis. The youngest child in this group was 12-mo-old. Ten (55.55 %) children were less than 24 mo of age. Significant sensitization to mites was detected in 7 (14.28 %) children with eczema. All children were below 24 mo of age. In children with a tendency to wheeze frequently without any evidence of infections or other systemic disease, 24 (48.9 %) had sensitization to HDM. The youngest child was 15 mo of age. Ten (41.6 %) children were below 24 mo of age. Sensitivity to Blomia tropicalis was detected in 6 (12.24 %) children. Significantly more number of children were sensitive to D. pteronyssinus as compared to D. farinae (65.31 % vs. 46.94 %; p = 0.034). CONCLUSIONS: Children in Mumbai show early sensitization to HDM. D. pteronyssinus is the commonest offending allergen in the index study.
OBJECTIVE: To identify house dust mite (HDM) sensitivity by skin prick test in children with allergic rhinitis, allergic wheezing and eczema. METHODS: In this prospective study, children with persistent or recurrent allergic symptoms of rhinitis, wheezing and eczema were enrolled to undergo skin prick testing. Sensitivity was checked for three mites: Dermatophagoide farinae, Dermatophagoide pteronyssinus, and Blomia tropicalis. RESULTS: Total 92 children underwent skin prick test; 49 (53.2 %) showed significant positivity to one or more dust mite. In the HDM sensitized group, a positive family history of allergic disorders was present in 32 children (65.3 %). In the HDM sensitized group, 18 (36.7 %) children had allergic rhinitis. The youngest child in this group was 12-mo-old. Ten (55.55 %) children were less than 24 mo of age. Significant sensitization to mites was detected in 7 (14.28 %) children with eczema. All children were below 24 mo of age. In children with a tendency to wheeze frequently without any evidence of infections or other systemic disease, 24 (48.9 %) had sensitization to HDM. The youngest child was 15 mo of age. Ten (41.6 %) children were below 24 mo of age. Sensitivity to Blomia tropicalis was detected in 6 (12.24 %) children. Significantly more number of children were sensitive to D. pteronyssinus as compared to D. farinae (65.31 % vs. 46.94 %; p = 0.034). CONCLUSIONS:Children in Mumbai show early sensitization to HDM. D. pteronyssinus is the commonest offending allergen in the index study.
Entities:
Keywords:
Blomia tropicalis; House dust mites; Sensitization
Authors: Juan C Celedón; Donald K Milton; Clare D Ramsey; Augusto A Litonjua; Louise Ryan; Thomas A E Platts-Mills; Diane R Gold Journal: J Allergy Clin Immunol Date: 2007-05-15 Impact factor: 10.793
Authors: Jay Portnoy; Jeffrey D Miller; P Brock Williams; Ginger L Chew; J David Miller; Fares Zaitoun; Wanda Phipatanakul; Kevin Kennedy; Charles Barnes; Carl Grimes; Désirée Larenas-Linnemann; James Sublett; David Bernstein; Joann Blessing-Moore; David Khan; David Lang; Richard Nicklas; John Oppenheimer; Christopher Randolph; Diane Schuller; Sheldon Spector; Stephen A Tilles; Dana Wallace Journal: Ann Allergy Asthma Immunol Date: 2013-12 Impact factor: 6.347
Authors: G Roberts; H Zhang; W Karmaus; A Raza; M Scott; S Matthews; R J Kurukulaaratchy; T Dean; S H Arshad Journal: Clin Exp Allergy Date: 2012-10 Impact factor: 5.018
Authors: S P Squillace; R B Sporik; G Rakes; N Couture; A Lawrence; S Merriam; J Zhang; A E Platts-Mills Journal: Am J Respir Crit Care Med Date: 1997-12 Impact factor: 21.405