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Literature DB >> 26663189

microRNA and Wound Healing.

Abstract

microRNAs (miRNAs) are small noncoding RNA molecules which play pivotal roles in wound healing. The increased expression of certain genes and expression of some others represent a key component of the wound biology and are largely under the regulation of naturally occurring miRNAs. Understanding the dysregulated miRNAs in chronic wound biology will therefore enable the development of newer therapies. This chapter focuses on the miRNAs that can be potentially targeted for improving skin wound healing and the challenges in miRNA therapy, including considerations in miRNA target identification and delivery.

Entities: CellLine Chemical Disease Gene Species

Keywords: Angiogenesis; HypoxymiRs; Inflammation; Re-epithelialization; Wound healing

Mesh：

Substances：

Year: 2015 PMID： 26663189 PMCID： PMC5096456 DOI： 10.1007/978-3-319-22671-2_15

Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622

66 in total

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Authors: J Weiler; J Hunziker; J Hall
Journal: Gene Ther Date: 2006-03 Impact factor: 5.250

2. Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis.

Authors: Angelika Kuehbacher; Carmen Urbich; Andreas M Zeiher; Stefanie Dimmeler
Journal: Circ Res Date: 2007-05-31 Impact factor: 17.367

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Journal: J Biol Chem Date: 2012-06-28 Impact factor: 5.157

4. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses.

Authors: Konstantin D Taganov; Mark P Boldin; Kuang-Jung Chang; David Baltimore
Journal: Proc Natl Acad Sci U S A Date: 2006-08-02 Impact factor: 11.205

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Authors: T F Slater
Journal: Biochem J Date: 1984-08-15 Impact factor: 3.857

6. Pharmacokinetics of phosphorothioate antisense oligodeoxynucleotides.

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Journal: Curr Opin Investig Drugs Date: 2001-04

7. MicroRNAs in resolution of acute inflammation: identification of novel resolvin D1-miRNA circuits.

Authors: Antonio Recchiuti; Sriram Krishnamoorthy; Gabrielle Fredman; Nan Chiang; Charles N Serhan
Journal: FASEB J Date: 2010-10-18 Impact factor: 5.191

Review 8. Redox signaling and the emerging therapeutic potential of thiol antioxidants.

Authors: C K Sen
Journal: Biochem Pharmacol Date: 1998-06-01 Impact factor: 5.858

9. MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by down-regulation of DC-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN).

Authors: Rocio T Martinez-Nunez; Fethi Louafi; Peter S Friedmann; Tilman Sanchez-Elsner
Journal: J Biol Chem Date: 2009-04-22 Impact factor: 5.157

Review 10. Oxygen sensors at the crossroad of metabolism.

Authors: Julián Aragonés; Peter Fraisl; Myriam Baes; Peter Carmeliet
Journal: Cell Metab Date: 2009-01-07 Impact factor: 27.287

22 in total

1. Local Immunomodulation Using an Adhesive Hydrogel Loaded with miRNA-Laden Nanoparticles Promotes Wound Healing.

Authors: Bahram Saleh; Harkiranpreet Kaur Dhaliwal; Roberto Portillo-Lara; Ehsan Shirzaei Sani; Reza Abdi; Mansoor M Amiji; Nasim Annabi
Journal: Small Date: 2019-07-22 Impact factor: 13.281

2. HIF1α/miR-199a/ADM feedback loop modulates the proliferation of human dermal microvascular endothelial cells (HDMECs) under hypoxic condition.

Authors: Yang Sun; Xiang Xiong; Xiancheng Wang
Journal: Cell Cycle Date: 2019-09-19 Impact factor: 4.534

Review 3. Plasma treatments of dressings for wound healing: a review.

Authors: Nithya Eswaramoorthy; David R McKenzie
Journal: Biophys Rev Date: 2017-10-02

4. HIF1A promotes miR-210/miR-424 transcription to modulate the angiogenesis in HUVECs and HDMECs via sFLT1 under hypoxic stress.

Authors: Haifu Zhao; Xiancheng Wang; Bairong Fang
Journal: Mol Cell Biochem Date: 2022-04-29 Impact factor: 3.396

Review 5. Chronic wounds.

Authors: Vincent Falanga; Roslyn Rivkah Isseroff; Athena M Soulika; Marco Romanelli; David Margolis; Suzanne Kapp; Mark Granick; Keith Harding
Journal: Nat Rev Dis Primers Date: 2022-07-21 Impact factor: 65.038

6. MiR-31 Mediates Inflammatory Signaling to Promote Re-Epithelialization during Skin Wound Healing.

Authors: Jianyun Shi; Xianghui Ma; Yang Su; Yongli Song; Yuhua Tian; Shukai Yuan; Xiuqing Zhang; Dong Yang; Hao Zhang; Jianwei Shuai; Wei Cui; Fazheng Ren; Maksim V Plikus; Yaoxing Chen; Jie Luo; Zhengquan Yu
Journal: J Invest Dermatol Date: 2018-03-30 Impact factor: 8.551

Review 10. MicroRNAs in metabolism.

Authors: S Vienberg; J Geiger; S Madsen; L T Dalgaard
Journal: Acta Physiol (Oxf) Date: 2016-04-05 Impact factor: 6.311