Literature DB >> 2666172

Substrate structural requirements of Schizosaccharomyces pombe RNase P.

D Drainas1, S Zimmerly, I Willis, D Söll.   

Abstract

RNase P from Schizosaccharomyces pombe has been purified over 2000-fold. The apparent Km for two S. pombe tRNA precursors derived from the supS1 and sup3-e tRNA(Ser) genes is 20 nM; the apparent Vmax is 2.5 nM/min (supS1) and 1.1 nM/min (sup3-e). Processing studies with precursors of other mutants show that the structures of the acceptor stem and anticodon/intron loop of tRNA are crucial for S. pombe RNase P action.

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Year:  1989        PMID: 2666172     DOI: 10.1016/0014-5793(89)81433-4

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  11 in total

1.  Effect of peptidyltransferase inhibitors on ribonuclease P activity from Dictyostelium discoideum. Effect of antibiotics on RNase P.

Authors:  C Stathopoulos; A Tsagla; A Tekos; D Drainas
Journal:  Mol Biol Rep       Date:  2000-06       Impact factor: 2.316

2.  Characterization of two scleroderma autoimmune antigens that copurify with human ribonuclease P.

Authors:  P S Eder; R Kekuda; V Stolc; S Altman
Journal:  Proc Natl Acad Sci U S A       Date:  1997-02-18       Impact factor: 11.205

3.  Regulated expression of functional external guide sequences in mammalian cells using a U6 RNA polymerase III promoter.

Authors:  Elizaveta Kovrigina; Li Yang; Emmanuel Pfund; Sidney Altman
Journal:  RNA       Date:  2005-08-30       Impact factor: 4.942

4.  The processing of wild type and mutant forms of rat nuclear pre-tRNA(Lys) by the homologous RNase P.

Authors:  T E Paisley; G C Van Tuyle
Journal:  Nucleic Acids Res       Date:  1994-08-25       Impact factor: 16.971

5.  Rpp1, an essential protein subunit of nuclear RNase P required for processing of precursor tRNA and 35S precursor rRNA in Saccharomyces cerevisiae.

Authors:  V Stolc; S Altman
Journal:  Genes Dev       Date:  1997-11-01       Impact factor: 11.361

6.  RNase P cleaves transient structures in some riboswitches.

Authors:  Sidney Altman; Donna Wesolowski; Cecilia Guerrier-Takada; Yong Li
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-01       Impact factor: 11.205

7.  Footprinting analysis demonstrates extensive similarity between eukaryotic RNase P and RNase MRP holoenzymes.

Authors:  Olga Esakova; Anna Perederina; Chao Quan; Mark E Schmitt; Andrey S Krasilnikov
Journal:  RNA       Date:  2008-06-25       Impact factor: 4.942

8.  Rpp2, an essential protein subunit of nuclear RNase P, is required for processing of precursor tRNAs and 35S precursor rRNA in Saccharomyces cerevisiae.

Authors:  V Stolc; A Katz; S Altman
Journal:  Proc Natl Acad Sci U S A       Date:  1998-06-09       Impact factor: 11.205

9.  Inhibition of viral gene expression by human ribonuclease P.

Authors:  D Kawa; J Wang; Y Yuan; F Liu
Journal:  RNA       Date:  1998-11       Impact factor: 4.942

10.  Rp-phosphorothioate modifications in RNase P RNA that interfere with tRNA binding.

Authors:  W D Hardt; J M Warnecke; V A Erdmann; R K Hartmann
Journal:  EMBO J       Date:  1995-06-15       Impact factor: 11.598

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