Kevin B Johnson1, Barron L Patterson2, Yun-Xian Ho3, Qingxia Chen4, Hui Nian5, Coda L Davison3, Jason Slagle6, Shelagh A Mulvaney7. 1. Department of Biomedical Informatics at Vanderbilt University School of Medicine, Nashville, TN, USA Department of Pediatrics at Vanderbilt University School of Medicine, Nashville, TN, USA kevin.johnson@vanderbilt.edu. 2. Department of Pediatrics at Vanderbilt University School of Medicine, Nashville, TN, USA. 3. Department of Biomedical Informatics at Vanderbilt University School of Medicine, Nashville, TN, USA. 4. Department of Biomedical Informatics at Vanderbilt University School of Medicine, Nashville, TN, USA Department of Biostatistics at Vanderbilt University School of Medicine, Nashville, TN, USA. 5. Department of Biostatistics at Vanderbilt University School of Medicine, Nashville, TN, USA. 6. Department of Anesthesiology at Vanderbilt University School of Medicine, Nashville, TN, USA. 7. Department of Biomedical Informatics at Vanderbilt University School of Medicine, Nashville, TN, USA School of Nursing at Vanderbilt University School of Medicine, Nashville, TN, USA.
Abstract
OBJECTIVE: Personal health applications have the potential to help patients with chronic disease by improving medication adherence, self-efficacy, and quality of life. The goal of this study was to assess the impact of MyMediHealth (MMH) - a website and a short messaging service (SMS)-based reminder system - on medication adherence and perceived self-efficacy in adolescents with asthma. METHODS: We conducted a block-randomized controlled study in academic pediatric outpatient settings. There were 98 adolescents enrolled. Subjects who were randomized to use MMH were asked to create a medication schedule and receive SMS reminders at designated medication administration times for 3 weeks. Control subjects received action lists as a part of their usual care. Primary outcome measures included MMH usage patterns and self-reports of system usability, medication adherence, asthma control, self-efficacy, and quality of life. RESULTS:Eighty-nine subjects completed the study, of whom 46 were randomized to the intervention arm. Compared to controls, we found improvements in self-reported medication adherence (P = .011), quality of life (P = .037), and self-efficacy (P = .016). Subjects reported high satisfaction with MMH; however, the level of system usage varied widely, with lower use among African American patients. CONCLUSIONS:MMH was associated with improved medication adherence, perceived quality of life, and self-efficacy.Trial Registration This project was registered under http://clinicaltrials.gov/ identifier NCT01730235.
RCT Entities:
OBJECTIVE: Personal health applications have the potential to help patients with chronic disease by improving medication adherence, self-efficacy, and quality of life. The goal of this study was to assess the impact of MyMediHealth (MMH) - a website and a short messaging service (SMS)-based reminder system - on medication adherence and perceived self-efficacy in adolescents with asthma. METHODS: We conducted a block-randomized controlled study in academic pediatric outpatient settings. There were 98 adolescents enrolled. Subjects who were randomized to use MMH were asked to create a medication schedule and receive SMS reminders at designated medication administration times for 3 weeks. Control subjects received action lists as a part of their usual care. Primary outcome measures included MMH usage patterns and self-reports of system usability, medication adherence, asthma control, self-efficacy, and quality of life. RESULTS: Eighty-nine subjects completed the study, of whom 46 were randomized to the intervention arm. Compared to controls, we found improvements in self-reported medication adherence (P = .011), quality of life (P = .037), and self-efficacy (P = .016). Subjects reported high satisfaction with MMH; however, the level of system usage varied widely, with lower use among African American patients. CONCLUSIONS: MMH was associated with improved medication adherence, perceived quality of life, and self-efficacy.Trial Registration This project was registered under http://clinicaltrials.gov/ identifier NCT01730235.
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