Literature DB >> 26661454

The CRISPR revolution and its impact on cancer research.

Ram Kannan1, Andrea Ventura2.   

Abstract

A revolution in cancer research is underway. Spurred by the advent of the CRISPR-Cas9 technology, new methods to probe the mammalian genomes are being developed. By providing simple, flexible, and cost-effective ways to edit and manipulate the genome of somatic cells of adult animals, these new methods present the opportunity to model cancer progression in vivo with an unprecedented degree of sophistication. Here we provide a brief overview of this exciting and fast-moving field.

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Year:  2015        PMID： 26661454      PMCID： PMC5512432          DOI： 10.4414/smw.2015.14230

Source DB:  PubMed          Journal:  Swiss Med Wkly        ISSN： 0036-7672            Impact factor:   2.193


  59 in total

1.  Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in Mice.

Authors:  Katerina Kraft; Sinje Geuer; Anja J Will; Wing Lee Chan; Christina Paliou; Marina Borschiwer; Izabela Harabula; Lars Wittler; Martin Franke; Daniel M Ibrahim; Bjørt K Kragesteen; Malte Spielmann; Stefan Mundlos; Darío G Lupiáñez; Guillaume Andrey
Journal:  Cell Rep       Date:  2015-02-07       Impact factor: 9.423

2.  Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.

Authors:  Pawel K Mazur; Alexander Herner; Stephano S Mello; Matthias Wirth; Simone Hausmann; Francisco J Sánchez-Rivera; Shane M Lofgren; Timo Kuschma; Stephan A Hahn; Deepak Vangala; Marija Trajkovic-Arsic; Aayush Gupta; Irina Heid; Peter B Noël; Rickmer Braren; Mert Erkan; Jörg Kleeff; Bence Sipos; Leanne C Sayles; Mathias Heikenwalder; Elisabeth Heßmann; Volker Ellenrieder; Irene Esposito; Tyler Jacks; James E Bradner; Purvesh Khatri; E Alejandro Sweet-Cordero; Laura D Attardi; Roland M Schmid; Guenter Schneider; Julien Sage; Jens T Siveke
Journal:  Nat Med       Date:  2015-09-21       Impact factor: 53.440

Review 3.  High-throughput functional genomics using CRISPR-Cas9.

Authors:  Ophir Shalem; Neville E Sanjana; Feng Zhang
Journal:  Nat Rev Genet       Date:  2015-04-09       Impact factor: 53.242

4.  Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development.

Authors:  E C Collins; R Pannell; E M Simpson; A Forster; T H Rabbitts
Journal:  EMBO Rep       Date:  2000-08       Impact factor: 8.807

5.  Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

Authors:  Yuyu Niu; Bin Shen; Yiqiang Cui; Yongchang Chen; Jianying Wang; Lei Wang; Yu Kang; Xiaoyang Zhao; Wei Si; Wei Li; Andy Peng Xiang; Jiankui Zhou; Xuejiang Guo; Ye Bi; Chenyang Si; Bian Hu; Guoying Dong; Hong Wang; Zuomin Zhou; Tianqing Li; Tao Tan; Xiuqiong Pu; Fang Wang; Shaohui Ji; Qi Zhou; Xingxu Huang; Weizhi Ji; Jiahao Sha
Journal:  Cell       Date:  2014-01-30       Impact factor: 41.582

Review 6.  lincRNAs: genomics, evolution, and mechanisms.

Authors:  Igor Ulitsky; David P Bartel
Journal:  Cell       Date:  2013-07-03       Impact factor: 41.582

7.  Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient-Derived iPSCs Using CRISPR-Cas9.

Authors:  Chul-Yong Park; Duk Hyoung Kim; Jeong Sang Son; Jin Jea Sung; Jaehun Lee; Sangsu Bae; Jong-Hoon Kim; Dong-Wook Kim; Jin-Soo Kim
Journal:  Cell Stem Cell       Date:  2015-07-23       Impact factor: 24.633

8.  Targeted genomic rearrangements using CRISPR/Cas technology.

Authors:  Peter S Choi; Matthew Meyerson
Journal:  Nat Commun       Date:  2014-04-24       Impact factor: 14.919

9.  Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing.

Authors:  Dirk Heckl; Monika S Kowalczyk; David Yudovich; Roger Belizaire; Rishi V Puram; Marie E McConkey; Anne Thielke; Jon C Aster; Aviv Regev; Benjamin L Ebert
Journal:  Nat Biotechnol       Date:  2014-06-22       Impact factor: 54.908

10.  RNA-guided gene activation by CRISPR-Cas9-based transcription factors.

Authors:  Pablo Perez-Pinera; D Dewran Kocak; Christopher M Vockley; Andrew F Adler; Ami M Kabadi; Lauren R Polstein; Pratiksha I Thakore; Katherine A Glass; David G Ousterout; Kam W Leong; Farshid Guilak; Gregory E Crawford; Timothy E Reddy; Charles A Gersbach
Journal:  Nat Methods       Date:  2013-07-25       Impact factor: 28.547
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  7 in total

Review 1.  Somatic Engineering of Oncogenic Chromosomal Rearrangements: A Perspective.

Authors:  Danilo Maddalo; Andrea Ventura
Journal:  Cancer Res       Date:  2016-08-12       Impact factor: 12.701

Review 2.  Cancer diagnosis and immunotherapy in the age of CRISPR.

Authors:  Peter J Cook; Andrea Ventura
Journal:  Genes Chromosomes Cancer       Date:  2018-12-20       Impact factor: 5.006

Review 3.  CRISPR-Cas9: from Genome Editing to Cancer Research.

Authors:  Si Chen; Heng Sun; Kai Miao; Chu-Xia Deng
Journal:  Int J Biol Sci       Date:  2016-11-04       Impact factor: 6.580

Review 4.  Modeling the process of human tumorigenesis.

Authors:  Sneha Balani; Long V Nguyen; Connie J Eaves
Journal:  Nat Commun       Date:  2017-05-25       Impact factor: 14.919

5.  Advent of CRISPR Based Immunotherapy in Hematologic Malignancies.

Authors:  R K Perez; R Chen; R Kang; A R Perez
Journal:  J Oncopathol Clin Res       Date:  2018-03-30

Review 6.  New insights on CRISPR/Cas9-based therapy for breast Cancer.

Authors:  Hussein Sabit; Shaimaa Abdel-Ghany; Huseyin Tombuloglu; Emre Cevik; Amany Alqosaibi; Fatma Almulhim; Afnan Al-Muhanaa
Journal:  Genes Environ       Date:  2021-04-29

7.  Safety and Efficacy of AAV Retrograde Pancreatic Ductal Gene Delivery in Normal and Pancreatic Cancer Mice.

Authors:  Kayla A Quirin; Jason J Kwon; Arafat Alioufi; Tricia Factora; Constance J Temm; Max Jacobsen; George E Sandusky; Kim Shontz; Louis G Chicoine; K Reed Clark; Joshua T Mendell; Murray Korc; Janaiah Kota
Journal:  Mol Ther Methods Clin Dev       Date:  2017-09-30       Impact factor: 6.698
  7 in total

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