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Literature DB >> 26659016

Bringing genetic background into focus.

Abstract

Researchers should embrace differences in genetic background to build richer disease models that more accurately reflect the level of variation in the human population, posits Clement Chow.

Entities: Species

Mesh：

Year: 2015 PMID： 26659016 DOI： 10.1038/nrg.2015.9

Source DB: PubMed Journal: Nat Rev Genet ISSN： 1471-0056 Impact factor: 53.242

7 in total

1. Ten years of the Collaborative Cross.

Authors: David W Threadgill; Gary A Churchill
Journal: Genetics Date: 2012-02 Impact factor: 4.562

2. Candidate genetic modifiers of retinitis pigmentosa identified by exploiting natural variation in Drosophila.

Authors: Clement Y Chow; Keegan J P Kelsey; Mariana F Wolfner; Andrew G Clark
Journal: Hum Mol Genet Date: 2015-12-11 Impact factor: 6.150

Review 3. Cystic fibrosis genetics: from molecular understanding to clinical application.

Authors: Garry R Cutting
Journal: Nat Rev Genet Date: 2014-11-18 Impact factor: 53.242

4. Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance.

Authors: Angela L Rasmussen; Atsushi Okumura; Martin T Ferris; Richard Green; Friederike Feldmann; Sara M Kelly; Dana P Scott; David Safronetz; Elaine Haddock; Rachel LaCasse; Matthew J Thomas; Pavel Sova; Victoria S Carter; Jeffrey M Weiss; Darla R Miller; Ginger D Shaw; Marcus J Korth; Mark T Heise; Ralph S Baric; Fernando Pardo-Manuel de Villena; Heinz Feldmann; Michael G Katze
Journal: Science Date: 2014-10-30 Impact factor: 47.728

5. SCNM1, a putative RNA splicing factor that modifies disease severity in mice.

Authors: David A Buchner; Michelle Trudeau; Miriam H Meisler
Journal: Science Date: 2003-08-15 Impact factor: 47.728

6. The Drosophila genome nexus: a population genomic resource of 623 Drosophila melanogaster genomes, including 197 from a single ancestral range population.

Authors: Justin B Lack; Charis M Cardeno; Marc W Crepeau; William Taylor; Russell B Corbett-Detig; Kristian A Stevens; Charles H Langley; John E Pool
Journal: Genetics Date: 2015-01-27 Impact factor: 4.562

7. The genetic architecture of the genome-wide transcriptional response to ER stress in the mouse.

Authors: Clement Y Chow; Xu Wang; David Riccardi; Mariana F Wolfner; Andrew G Clark
Journal: PLoS Genet Date: 2015-02-04 Impact factor: 5.917

7 in total

18 in total

1. A genetic model to study O-GlcNAc cycling in immortalized mouse embryonic fibroblasts.

Authors: Melissa M St Amand; Michelle R Bond; Julia Riedy; Marcella Comly; Joseph Shiloach; John A Hanover
Journal: J Biol Chem Date: 2018-06-28 Impact factor: 5.157

2. Identifying natural genotypes of grain number per panicle in rice (Oryza sativa L.) by association mapping.

Authors: Jianyin Xie; Fengmei Li; Najeeb Ullah Khan; Xiaoyang Zhu; Xueqiang Wang; Zhifang Zhang; Xiaoqian Ma; Yan Zhao; Quan Zhang; Shuyang Zhang; Zhanying Zhang; Jinjie Li; Zichao Li; Hongliang Zhang
Journal: Genes Genomics Date: 2018-11-19 Impact factor: 1.839

3. Using Drugs to Probe the Variability of Trans-Epithelial Airway Resistance.

Authors: Kendra Tosoni; Diane Cassidy; Barry Kerr; Stephen C Land; Anil Mehta
Journal: PLoS One Date: 2016-02-29 Impact factor: 3.240

Review 4. Translational Rodent Models for Research on Parasitic Protozoa-A Review of Confounders and Possibilities.

Authors: Totta Ehret; Francesca Torelli; Christian Klotz; Amy B Pedersen; Frank Seeber
Journal: Front Cell Infect Microbiol Date: 2017-06-07 Impact factor: 5.293

5. Genomic analyses identify multiple Asian origins and deeply diverged mitochondrial clades in inbred brown rats (Rattus norvegicus).

Authors: Emily E Puckett; Olivia Micci-Smith; Jason Munshi-South
Journal: Evol Appl Date: 2017-12-07 Impact factor: 5.183

6. Natural Genetic Variation Screen in Drosophila Identifies Wnt Signaling, Mitochondrial Metabolism, and Redox Homeostasis Genes as Modifiers of Apoptosis.

Authors: Rebecca A S Palu; Elaine Ong; Kaitlyn Stevens; Shani Chung; Katie G Owings; Alan G Goodman; Clement Y Chow
Journal: G3 (Bethesda) Date: 2019-12-03 Impact factor: 3.154