Literature DB >> 26658807

A Bloody Mess: An Unusual Case of Diffuse Alveolar Hemorrhage Because of Warfarin Overdose.

Enrico Heffler1, Raffaele Campisi, Sebastian Ferri, Nunzio Crimi.   

Abstract

We herein present the case of a patient with frank hemoptysis and hematuria, dyspnea, and cough. The patient was known to be affected by Chronic Obstructive Pulmonary Disease (COPD) and dilated cardiomyopathy with atrial fibrillation. For this latter condition, he was supposed to take 1.25 mg warfarin daily. Laboratory findings revealed very high levels of International Normalized Ratio (INR) (16), and the patient referred that he self-increased warfarin dose to 5 mg daily since 8 days before the onset of symptoms. Computed tomography scan revealed diffuse bilateral signs of alveolar hemorrhage with hydroaerial levels within emphysematous cysts. Wafarin was immediately stopped and changed with 220 mg dabigatran daily, and he was properly treated to restore a normal coagulation status. We concluded for a case of diffuse alveolar hemorrhage because of warfarin overdose.

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Year:  2016        PMID: 26658807     DOI: 10.1097/MJT.0000000000000397

Source DB:  PubMed          Journal:  Am J Ther        ISSN: 1075-2765            Impact factor:   2.688


  3 in total

1.  Warfarin maintenance dose Prediction for Patients undergoing heart valve replacement- a hybrid model with genetic algorithm and Back-Propagation neural network.

Authors:  Qian Li; Huan Tao; Jing Wang; Qin Zhou; Jie Chen; Wen Zhe Qin; Li Dong; Bo Fu; Jiang Long Hou; Jin Chen; Wei-Hong Zhang
Journal:  Sci Rep       Date:  2018-06-26       Impact factor: 4.379

2.  Percutaneous Left Atrial Appendage Closure in a Patient with Diffuse Alveolar Hemorrhaging Associated with Anticoagulant Therapy and Atrial Fibrillation.

Authors:  Takaaki Ogoshi; Masato Fukunaga; Yu Suzuki; Yusuke Taura; Kazuhiro Yatera
Journal:  Intern Med       Date:  2021-11-27       Impact factor: 1.282

3.  Warfarin-induced diffuse alveolar hemorrhage: Case report and a review of the literature.

Authors:  Shekhar Kunal; Rajeev Bagarhatta; Sheetu Singh; Sohan Kumar Sharma
Journal:  Lung India       Date:  2019 Nov-Dec
  3 in total

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