Literature DB >> 26656650

Ethics of children's participation in a Saudi biobank: an exploratory survey.

Ghiath Alahmad1,2, Tamer Hifnawy3,4, Kris Dierickx5.   

Abstract

PURPOSE: The aim of this study was to investigate the ethical issues involved in children's participation in research biobanks in Saudi Arabia and the Middle East.
METHODS: A survey of 160 respondents from four groups (researchers, physicians, medical students, and laypersons) was conducted at King Abdulaziz Medical City in Riyadh, Saudi Arabia.
RESULTS: A clear and positive attitude toward pediatric clinical and genetic research inside and outside of Saudi Arabia was found. Parental consent is viewed as essential, with 60% saying parental consent is sufficient for children up to 12, and 40% saying it is sufficient for children 12-18 years old. More than 90% of respondents preferred to gain approval from any child with a decision-making capability; 58.2 and 38.6% of them believed that children between 12 and 18, and >18 years of age, respectively, can understand and thus give their approval for genetic research. Clear majorities in the study agreed with re-consenting children when they become adults, allowing them to withdraw at any time. A clear majority agreed that either parent could sign a consent form for their child to participate in a research biobank.
CONCLUSION: All four groups believed, to varying degrees, that elements of ethical consideration were critical when involving children in research.Genet Med 18 8, 806-813.

Entities:  

Mesh:

Year:  2015        PMID: 26656650     DOI: 10.1038/gim.2015.164

Source DB:  PubMed          Journal:  Genet Med        ISSN: 1098-3600            Impact factor:   8.822


  27 in total

1.  Drug company sued over research trial in Nigeria.

Authors:  K Ahmad
Journal:  Lancet       Date:  2001-09-08       Impact factor: 79.321

2.  An exploratory survey of professionals on the use of stored tissue samples from minors for genetic research.

Authors:  K Hens; J Snoeck; H Nys; J-J Cassiman; K Dierickx
Journal:  Genet Mol Res       Date:  2010-05-25

Review 3.  Genetic research on stored tissue samples from minors: a systematic review of the ethical literature.

Authors:  Kristien Hens; Herman Nys; Jean-Jacques Cassiman; Kris Dierickx
Journal:  Am J Med Genet A       Date:  2009-10       Impact factor: 2.802

4.  Research ethics. Children and population biobanks.

Authors:  David Gurwitz; Isabel Fortier; Jeantine E Lunshof; Bartha Maria Knoppers
Journal:  Science       Date:  2009-08-14       Impact factor: 47.728

5.  Public attitude towards biomedical research at outpatient clinics of King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Authors:  M Al-Jumah; M A Abolfotouh; I B Alabdulkareem; H H Balkhy; M I Al-Jeraisy; A F Al-Swaid; E M Al-Musaaed; B Al-Knawy
Journal:  East Mediterr Health J       Date:  2011-06       Impact factor: 1.628

6.  Paediatric biobanks: what makes them so unique?

Authors:  Julie Samuël; Bartha M Knoppers; Denise Avard
Journal:  J Paediatr Child Health       Date:  2011-04-29       Impact factor: 1.954

7.  Confidentiality, informed consent, and children's participation in research involving stored tissue samples: interviews with medical professionals from the Middle East.

Authors:  Ghiath Alahmad; Mohammed Al Jumah; Kris Dierickx
Journal:  Narrat Inq Bioeth       Date:  2015

8.  Pediatric biobanks: approaching informed consent for continuing research after children grow up.

Authors:  Aaron J Goldenberg; Sara Chandros Hull; Jeffrey R Botkin; Benjamin S Wilfond
Journal:  J Pediatr       Date:  2009-10       Impact factor: 4.406

9.  Adolescent carrier testing in practice: the impact of legal rulings and problems with "gillick competence".

Authors:  Paula Boddington; Maggie Gregory
Journal:  J Genet Couns       Date:  2008-08-29       Impact factor: 2.537

10.  Ethical implications of including children in a large biobank for genetic-epidemiologic research: a qualitative study of public opinion.

Authors:  David Kaufman; Gail Geller; Lisa Leroy; Juli Murphy; Joan Scott; Kathy Hudson
Journal:  Am J Med Genet C Semin Med Genet       Date:  2008-02-15       Impact factor: 3.908

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