Cem Ozgonul1, Erdim Sertoglu2, Tarkan Mumcuoglu3, Gokhan Ozge3, Gokcen Gokce4. 1. a Van Military Hospital , Department of Ophthalmology , Van , Turkey. 2. b Ankara Mevki Military Hospital, Anittepe Dispensary , Biochemistry Laboratory , Ankara , Turkey. 3. c Gulhane Military Medical Academy , Department of Ophthalmology , Ankara , Turkey. 4. d Kayseri Military Hospital , Department of Ophthalmology , Kayseri , Turkey.
Abstract
PURPOSE: To assess the levels of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in patients with pseudoexfoliation syndrome (PEX) and to compare the NLR and PLR results of patients with PEX, PEX glaucoma (PXG), and healthy controls. METHODS: In total, 34 patients with PEX, 29 patients with PXG, and 42 healthy subjects were enrolled in this retrospective study. Complete ophthalmologic examination and complete blood count measurements were performed of all subjects. Complete blood counts were performed within 2 h of blood collection. RESULTS: There was a significant difference in NLR between PEX and control groups (p = 0.012) and PXG and control groups (p = 0.003). Also, a significant difference was found in PLR values between control and PXG groups (p = 0.024). CONCLUSIONS: Our study for the first time provides evidence that PLR and NLR may be useful for predicting the prognosis of PEX patients and progression to PXG.
PURPOSE: To assess the levels of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in patients with pseudoexfoliation syndrome (PEX) and to compare the NLR and PLR results of patients with PEX, PEX glaucoma (PXG), and healthy controls. METHODS: In total, 34 patients with PEX, 29 patients with PXG, and 42 healthy subjects were enrolled in this retrospective study. Complete ophthalmologic examination and complete blood count measurements were performed of all subjects. Complete blood counts were performed within 2 h of blood collection. RESULTS: There was a significant difference in NLR between PEX and control groups (p = 0.012) and PXG and control groups (p = 0.003). Also, a significant difference was found in PLR values between control and PXG groups (p = 0.024). CONCLUSIONS: Our study for the first time provides evidence that PLR and NLR may be useful for predicting the prognosis of PEX patients and progression to PXG.
Entities:
Keywords:
Glaucoma; inflammation; neutrophil to lymphocyte ratio; platelet to lymphocyte ratio; pseudoexfoliation syndrome
Authors: Funda Dikkaya; Sevil Karaman Erdur; Mustafa Ozsutcu; Rukiye Aydin; Mehmet Selim Kocabora; Cengiz Aras Journal: Int Ophthalmol Date: 2017-06-12 Impact factor: 2.031
Authors: Cem Ozgonul; Erdim Sertoglu; Onder Ayyildiz; Tarkan Mumcuoglu; Murat Kucukevcilioglu; Gokcen Gokce; Ali Hakan Durukan Journal: Int J Ophthalmol Date: 2017-02-18 Impact factor: 1.779