Literature DB >> 28251086

Novel biomarkers for patients with idiopathic acute anterior uveitis: neutrophil to lymphocyte ratio and platelet to lymphocyte ratio.

Cem Ozgonul1, Erdim Sertoglu2, Onder Ayyildiz3, Tarkan Mumcuoglu3, Murat Kucukevcilioglu3, Gokcen Gokce3, Ali Hakan Durukan3.   

Abstract

AIM: To assess the levels of the neutrophil to lymphocyte ratio (N/L) and the platelet to lymphocyte ratio (P/L) in patients with idiopathic acute anterior uveitis (AAU) and to compare with healthy controls.
METHODS: Thirty-six male patients with idiopathic AAU and 36 male healthy subjects were enrolled in this retrospective study. Complete ophthalmological examination and complete blood count measurements results of all subjects were evaluated.
RESULTS: There was a significant difference in N/L and P/L between idiopathic AAU and control groups (P=0.006, P=0.022). Also, correlation analysis revealed a significant correlation between C-reactive protein (CRP) and N/L (P=0.002; r=0.461).
CONCLUSION: Our study for the first time provides evidence of N/L and P/L may be useful biomarkers in patients with idiopathic AAU. N/L is correlated with CRP, so it can be a useful biomarker to predict the prognosis in idiopathic AAU.

Entities:  

Keywords:  C-reactive protein; inflammation; lymphocyte; neutrophil; platelet; uveitis

Year:  2017        PMID: 28251086      PMCID: PMC5313550          DOI: 10.18240/ijo.2017.02.13

Source DB:  PubMed          Journal:  Int J Ophthalmol        ISSN: 2222-3959            Impact factor:   1.779


  23 in total

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4.  Accurate Use of Neutrophil/Lymphocyte Ratio in Patients with Age-related Macular Degeneration.

Authors:  Cem Ozgonul; Erdim Sertoglu
Journal:  Ocul Immunol Inflamm       Date:  2014-10-27       Impact factor: 3.070

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Authors:  M Santos Lacomba; C Marcos Martín; J M Gallardo Galera; M A Gómez Vidal; E Collantes Estévez; R Ramírez Chamond; M Omar
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  7 in total

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4.  Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion.

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5.  Complete Blood Count-Derived Inflammation Indices and Retinal Vein Occlusion: A Case-Control Study.

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6.  Systemic immune-inflammation index could be associated with pseudophakic cystoid macular edema after an uneventful phacoemulsification surgery in patients without risk factors.

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7.  A Network of Serum Proteins Predict the Need for Systemic Immunomodulatory Therapy at Diagnosis in Noninfectious Uveitis.

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Journal:  Ophthalmol Sci       Date:  2022-05-31
  7 in total

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