Literature DB >> 26645106

Malignant meningitis secondary to oesophageal adenocarcinoma presenting with sensorineural hearing loss: a series of three cases and discussion of the literature.

Mark Adams1,2, Carolynne Doherty3, Anna O'Kane3, Samuel Hall3, Raeburn B Forbes4, Brian Herron5, Edward J McNaboe3.   

Abstract

Malignant meningitis may rarely present to the otolaryngologist. We report our experience with 3 patients presenting with sudden, progressive bilateral sensorineural hearing loss secondary to malignant meningitis. The primary tumour in all 3 cases was oesophageal adenocarcinoma. All 3 cases were notable for the rapidity of the patients' clinical deterioration; the interval from presentation to death ranged from 21 to 28 days. We suggest that otolaryngologists should remain vigilant to the possibility of this devastating diagnosis and have a low threshold for further investigation in patients with suspicious features. It is important to note that initial MRI and lumbar puncture may be negative and repeat testing should be undertaken if there is clinical suspicion.

Entities:  

Keywords:  Hearing loss; Malignant meningitis; Oesophageal cancer; Sensorineural hearing loss

Mesh:

Year:  2015        PMID: 26645106     DOI: 10.1007/s00405-015-3842-z

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  21 in total

1.  A case of meningeal carcinomatosis presenting with the primary symptoms of facial palsy and sensorineural deafness.

Authors:  Shunkichi Baba; Han Matsuda; Minoru Gotoh; Ken-Ichi Shimada; Yukiko Yokoyama; Atsuko Sakanushi
Journal:  J Nippon Med Sch       Date:  2006-08       Impact factor: 0.920

Review 2.  Pancreatic adenocarcinoma presenting with sudden onset bilateral deafness secondary to metastatic leptomeningeal infiltration.

Authors:  Samuel Joseph Blows; Richard Morgan; Umeet Dhariwal; Gemma Petts; Frederico Roncaroli
Journal:  Age Ageing       Date:  2012-06-27       Impact factor: 10.668

Review 3.  Leptomeningeal metastases from solid tumors (meningeal carcinomatosis).

Authors:  Michiko Kimura Bruno; Jeffrey Raizer
Journal:  Cancer Treat Res       Date:  2005

4.  Bilateral profound hearing loss due to meningeal carcinomatosis.

Authors:  Michiel Wagemakers; Wim Verhagen; Bas van de Borne; Dick Venderink; Carla Wauters; Luc Strobbe
Journal:  J Clin Neurosci       Date:  2005-04       Impact factor: 1.961

5.  Meningeal carcinomatosis: an unusual cause of deafness.

Authors:  M K Morgan; I Zammit-Maempel; J Hill
Journal:  J R Coll Surg Edinb       Date:  1998-04

6.  Carcinomatous meningitis appearing as acoustic neuromas: two cases.

Authors:  Sabrina T Astner; Carsten Nieder; Konrad Stock; Jochen Gaa; Anca Ligia Grosu
Journal:  Strahlenther Onkol       Date:  2007-05       Impact factor: 3.621

7.  Confusion and altered behaviour? Cause.

Authors:  Ronstan Lobo; Isweri Pillay; Barry Kennedy; Michael Watts
Journal:  BMJ Case Rep       Date:  2013-01-21

8.  Leptomeningeal carcinomatosis of gastric cancer misdiagnosed as vestibular schwannoma.

Authors:  Shin-Jae Kim; Jeong-Taik Kwon; Seog-Kyun Mun; Young-Ho Hong
Journal:  J Korean Neurosurg Soc       Date:  2014-07-31

9.  Meningeal carcinomatosis producing bilateral sudden hearing loss: a case report.

Authors:  F Civantos; Y S Choi; E L Applebaum
Journal:  Am J Otol       Date:  1992-07

10.  Diagnosis and treatment of leptomeningeal metastases from solid tumors: experience with 90 patients.

Authors:  W R Wasserstrom; J P Glass; J B Posner
Journal:  Cancer       Date:  1982-02-15       Impact factor: 6.860

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  2 in total

1.  Basic Analysis of the Cerebrospinal Fluid: An Important Framework for Laboratory Diagnostics of the Impairment of the Central Nervous System.

Authors:  Petr Kelbich; Karel Hrach; Jan Spicka; Petr Vachata; Tomas Radovnicky; Eva Hanuljakova; Jan Krejsek
Journal:  Curr Issues Mol Biol       Date:  2022-08-14       Impact factor: 2.976

2.  The association between comorbidities and inpatient mortality with sudden sensorineural hearing loss using a national database in Taiwan.

Authors:  Chao-Yin Kuo; Chi-Hsiang Chung; Chih-Hung Wang; Wu-Chien Chien; Hsin-Chien Chen
Journal:  J Int Med Res       Date:  2020-02       Impact factor: 1.671

  2 in total

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